Allergy to the cat—from diagnosis to management (original) (raw)

Abstract

Background In allergology practice, efficient counselling of cat owners is often frustrating because the topic of allergen avoidance is mostly a "no-go" and there are only few studies on allergen immunotherapy that prove its efficacy. In the end, what patients are mostly offered in allergy consultations are allergen reduction measures and symptomatic therapy. Results Sensitisation to the main cat allergen Fel d 1 occurs more frequently in atopic conditions and then represents a risk for allergic rhinitis and asthma. Current guidelines are therefore cautious about the firsttime acquisition of a cat in the first months of life in atopic families. However, sensitisation occurs in many cases even without contact with an own cat at home.

Figures (1)

Fig. 1 Decision tree in the allergologic consultation: Specific IgE anti-Fel d 1 and matching clinical symptoms enable the diagnosis of cat allergy. Besides symptomatic therapy, the reduction of allergen exposure is in the foreground. A Pre- scribed allergen abstinence mostly fails due to animal love, B in Switzerland, work is being done to develop a protocol for immunising the cat against Fel d 1 in order to induce neutralis- ing, feline anti-Fel d 1 IgG, C cat food containing chicken IgY anti-Fel d 1, which reduces the allergen excretion of the pet cat, is already commercially available, D allergen immunother- apy applies the specific cat allergen to induce allergen-spe- cific tolerance E developments of a human IgG4 anti-Fel d 1 biologic for passive immunotherapy in cat allergy are promis- ing; A-E are thus allergen-specific approaches, F An entirely allergen-nonspecific approach is dietary management using holoBLG lozenges counteracting cat allergy We concentrated on specifically compensating for this intracellular iron deficiency and thus correcting

Fig. 1 Decision tree in the allergologic consultation: Specific IgE anti-Fel d 1 and matching clinical symptoms enable the diagnosis of cat allergy. Besides symptomatic therapy, the reduction of allergen exposure is in the foreground. A Pre- scribed allergen abstinence mostly fails due to animal love, B in Switzerland, work is being done to develop a protocol for immunising the cat against Fel d 1 in order to induce neutralis- ing, feline anti-Fel d 1 IgG, C cat food containing chicken IgY anti-Fel d 1, which reduces the allergen excretion of the pet cat, is already commercially available, D allergen immunother- apy applies the specific cat allergen to induce allergen-spe- cific tolerance E developments of a human IgG4 anti-Fel d 1 biologic for passive immunotherapy in cat allergy are promis- ing; A-E are thus allergen-specific approaches, F An entirely allergen-nonspecific approach is dietary management using holoBLG lozenges counteracting cat allergy We concentrated on specifically compensating for this intracellular iron deficiency and thus correcting

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