Furopyrimidine derivatives as new wheat growth regulators. (original) (raw)

2024, VІІІ-ма Міжнародна науково-практична конференція «Наукові засади підвищення ефективності сільськогосподарського виробництва», 29 листопада 2024 р., Україна, Харків.

The regulatory effect of new furopyrimidine derivatives (compounds № 1 – 12) on wheat growth was compared with the effect of known synthetic compounds, derivatives of sodium and potassium salts of 6-methyl-2-mercapto-4-hydroxypyrimidine (Methyur, Kamethur) and plant hormone auxin IAA (1H-indol-3-yl)acetic acid). All chemical compounds studied in the work were synthesized at the Department for Chemistry of Bioactive Nitrogen-Containing Heterocyclic Compounds, V.P. Kukhar Institute of Bioorganic Chemistry and Petrochemistry of the National Academy of Sciences of Ukraine. Auxin IAA (1H-indol-3-yl)acetic acid) was manufactured by Sigma-Aldrich, USA. Morphometric parameters of wheat plants (average length of shoots (mm) and average length of roots (mm)) were measured after 4 weeks. Our current study revealed that new furopyrimidine derivatives exhibit a regulatory effect similar to the effect of auxin IAA and known synthetic compounds, derivatives of 6-methyl-2-mercapto-4-hydroxypyrimidine (Methyur, Kamethur) on the growth and development of wheat roots and shoots in the vegetative stage. Morphometric parameters of wheat plants (average length of roots (mm) and average length of shoots (mm)), treated with synthetic compounds, furopyrimidine derivatives in a concentration of 10-7M, significantly increased as compared to control wheat plants treated with distilled water. Their regulatory effect was similar to the effect of auxin IAA, or synthetic compounds, derivatives of sodium and potassium salts of 6-methyl-2-mercapto-4-hydroxypyrimidine (Methyur, Kamethur), which are known as auxin-like and cytokinin-like compounds due to their regulatory effect on the growth of plant shoots and roots. Analyzing the relationship between chemical structure and regulatory effect of synthetic compounds, furopyrimidine derivatives on the morphometric and biochemical parameters of wheat plants, it can be assumed that their regulatory effect on the growth and photosynthesis of wheat plants is related to the presence of substituents in their chemical structure. Based on the obtained morphometric parameters of wheat plants, it is possible to propose the practical use of synthetic compounds, derivatives of sodium and potassium salts of 6-methyl-2-mercapto-4-hydroxypyrimidine (Methyur, Kamethur), and most active furopyrimidine derivatives № 2 – 4, 6 – 12 in a concentration of 10-7M for improving the growth of roots and shoots in winter wheat (Triticum aestivum L.) variety Tyra during the vegetative stage.