分類不能の小児肺microcystic Parenchymal MALDEVELOPMENTの1例 (original) (raw)
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Haigan, 2004
Background. Metastasis from lung cancer to the spinal cord or the optic chiasm is rare. Case. A 65-year-old man was given a diagnosis as T1N2M0 localized small cell lung cancer. He responded well to systemic chemotherapy and radiotherapy. Seven months after the first admission, his brain MRI revealed multiple brain metastases, and whole brain irradiation was performed. Thirteen months after the first admission, he experienced paresis of his legs and bitemporal hemianopia. His spinal cord MRI revealed multiple intramedullary metastasis, and cerebrospinal fluid showed malignancy. Leptomeningeal metastasis from small cell lung cancer was diagnosed. Spinal cord irradiation was performed, and his lower limbs paresis improved slightly. His eyesight failed gradually, and brain MRI revealed optic chiasm metastasis. Optic chiasm irradiation was performed, but his eyesight deteriorated. Paralysis of his legs and his body gradually increased, and 18 months after the first admission, he died. Conclusion. We report a case of metastasis from small cell lung cancer to the spinal cord and the optic chiasm.
Haigan, 2002
Pleural invasion by tumor is an important prognostic factor in patients with non-smallcell lung cancer. Most p3 patients are considered T3, but adjacent lobe invasion beyond the interlobar pleura is categorized as T2. However, the outcome of patients with adjacent lobe invasion beyond the interlobar pleura is controversial. Methods. To investigate the prognosis of p3 patients including those with adjacent lobe invasion beyond the interlobar pleura, 40 patients who underwent pulmonary resection between 1988 and 1998 were reviewed. The subjects included 15 with adjacent lobe invasion beyond the interlobar pleura (Int. group), and 25 with invasion to other organs or tissue (Non-int. group). Results. The 5-year survival rate of the Int. group and the Non-int. group was 44.4% and 19.4%, respectively. There was no significant difference between the two groups. Conclusion. At this moment, the patients with adjacent lobe invasion beyond the interlobar pleura are not considered T2. Further studies of more cases are needed to obtain a statistically significant difference between Int. and Non-int. groups. (JJLC. 2002; 42: 163-167) KEY WORDS-Non-small-cell lung cancer, Pleural invasion, Interlobar pleural invasion