GRIM-19, a death-regulatory gene product, suppresses Stat3 activity via functional interaction (original) (raw)
The biological functions of the versatile transcription factors STAT3 and STAT5 and new strategies for their targeted inhibition
Sylvane Desrivieres
Journal of Mammary …, 2006
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STAT1 and STAT3 as intracellular regulators of vascular remodeling
Tomasz Hirnle
European Journal of Internal Medicine, 2007
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Signal Transducer and Activator of TRANSCRIPTION-3 (STAT3) and Psoriasis
Magda Assaf
Zagazig university medical journal, 2015
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Targeting STAT-3 signaling pathway in cancer for development of novel drugs: Advancements and challenges
ayesha butt
Genetics and Molecular Biology, 2020
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A Novel Sequence in the Coiled-coil Domain of Stat3 Essential for Its Nuclear Translocation
veronica diermayr
Journal of Biological Chemistry, 2003
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HiJAK'd Signaling; the STAT3 Paradox in Senescence and Cancer Progression
Damian Junk
Cancers (Basel), 2014
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Threes Company: Regulation of Cell Fate by Statins
Joannis Vamvakopoulos
Current drug targets, 2005
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NF-kB and STAT5 Play Important Roles in the Regulation of Mouse Toll-Like Receptor 2 Gene Expression1
Yasunobu Yoshikai
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STAT3β controls inflammatory responses and early tumor onset in skin and colon experimental cancer models
Valeria Poli
2014
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Stat5: from lactogenesis to tumorigenesis
Itamar Barash
Journal of Cancer Science & Therapy, 2013
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Activating mutations of STAT3: Impact on human growth
Mariana Gutiérrez
Molecular and Cellular Endocrinology, 2020
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JNK1/2 expression and modulation of STAT3 signaling in oral cancer
George Rassidakis
Oncology Letters, 2016
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Erk1/2 activation and modulation of STAT3 signaling in oral cancer
George Rassidakis
Oncology Reports, 2014
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Targeting Stat3 Induces Senescence in Tumor Cells and Elicits Prophylactic and Therapeutic Immune Responses against Breast Cancer Growth Mediated by NK Cells and CD4+T Cells
Cecilia Proietti
The Journal of Immunology, 2012
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Data from Multilayer OMIC Data in Medullary Thyroid Carcinoma Identifies the STAT3 Pathway as a Potential Therapeutic Target in <i>RET</i><sup>M918T</sup> Tumors
Salud Borrego
2023
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Stat5a and Stat5b Proteins Have Essential and Nonessential, or Redundant, Roles in Cytokine Responses
Stephan Teglund
Cell, 1998
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The cell death regulator GRIM19 is an inhibitor of signal transducer and activator of transcription 3
Valeria Poli
Proceedings of The National Academy of Sciences, 2003
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LLL12B, a small molecule STAT3 inhibitor, induces growth arrest, apoptosis, and enhances cisplatin-mediated cytotoxicity in medulloblastoma cells
Jonathan Finlay
Scientific Reports, 2021
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Quantitative specificity of STAT1 and several variants
Gary Stormo
Nucleic Acids Research, 2017
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If You Cannot Win Them, Join Them: Understanding New Ways to Target STAT3 by Small Molecules
Paola Jiménez
2019
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Programmed cell death in aging
John Tower
Ageing Research Reviews, 2015
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Novel STAT3 Target Genes Exert Distinct Roles in the Inhibition of Mesoderm and Endoderm Differentiation in Cooperation with Nanog
Pierre Savatier
Stem Cells, 2009
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RegulonDB (version 6.0): gene regulation model
Irma Martinez-Flores
2007
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The CATS (FAM64A) protein is a substrate of the Kinase Interacting Stathmin (KIS)
Fernanda Soares Niemann
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2013
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IL-7R–Dependent Phosphatidylinositol 3-Kinase Competes with the STAT5 Signal to Modulate T Cell Development and Homeostasis
Yasunobu Yoshikai
Journal of Immunology, 2020
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Mitochondrial Localized Stat3 Promotes Breast Cancer Growth via Phosphorylation of Serine 727
Edward Lesnefsky
Journal of Biological Chemistry, 2013
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General Nature of the STAT3-Activated Anti-Inflammatory Response
Kasmi Kasmi
The Journal of Immunology, 2006
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Hepatoprotective versus Oncogenic Functions of STAT3 in Liver Tumorigenesis
Fouad LAFDIL
The American Journal of Pathology, 2011
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Stat5 in breast cancer: potential oncogenic activity coincides with positive prognosis for the disease
Itamar Barash
Carcinogenesis, 2012
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Interaction of Stat6 and NF-kB: Direct Association and Synergistic Activation of Interleukin-4-Induced Transcription
Janet Stavnezer
1998
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Functional STAT3 deficiency compromises the generation of human T follicular helper cells
Dina Averbuch
2012
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NF-κB and STAT3 in glioblastoma: therapeutic targets coming of age
Susan Nozell
Expert Review of Neurotherapeutics, 2014
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Constitutive Activation of JAK3/STAT3 in Colon Carcinoma Tumors and Cell Lines
Raymond Lai
The American Journal of Pathology, 2005
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Critical role of STAT3 in melanoma metastasis through anoikis
Neel Fofaria
2016
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Genetic background determines if Stat5b suppresses or enhances murine hepatocarcinogenesis
Norman Drinkwater
Molecular Carcinogenesis, 2014
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