What do we know about COVID-19? A review article (original) (raw)

2020, Revista Da Associacao Medica Brasileira

COVID-19 Outbreak: Spread, Symptoms, Treatment and Research

BioMedica, 2020

The pandemic of COVID-19 (SARS CoV-2 or 2019-nCoV), a disease characterized by array of symptoms leading to severe acute respiratory problems, began in the Central Chinese city of Wuhan. 1 Wuhan is a city where almost 11 million people reside and it was hit by this pandemic in December 2019. Patients having this disease mostly suffered from respiratory disorders from a previously unknown causative agent. It was thought that this novel pathogen emerged from the seafood market of Wuhan. The causative agent is identified as a closely related member of severe acute respiratory syndrome Coronavirus (SARS-CoV). Coronaviruses family is a large family which contains several viruses including Middle East Respiratory Syndrome virus (MERS-CoV) besides SARS-CoV. The first case which was reported in Wuhan December 2019 had symptoms resembling to (SARS) and MERS. Historically this family of Corona viruses has had a major health and socio-economic impact. In 2003, the SARS-CoV caused 8096 infections worldwide with a case-fatality rate of 9.6% and a total 1.

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