Direkte Bindungen zwischen Metallatomen: Dimetallkomplexe von Zink, Cadmium und Quecksilber (original) (raw)

Metallkomplexe mit biologisch wichtigen Liganden, CLXI (1). Halbsandwich-Komplexe mit tert-Leucin, Dipeptiden, Pentaglycin und Glutathion als Liganden

Zeitschrift für Naturforschung. B, A journal of chemical sciences, 2005

AlaOMe with the chloro-bridged complexes [Cp * IrCl 2 ] 2 , [(p-cymene)RuCl 2 ] 2 or [(C 6 Me 6)RuCl 2 ] 2 in the presence of NaOMe give the complexes [Cp * Ir(Cl)NH 2 CH(R)CO 2 ] (1), [(p-cymene)Ru(Cl)-NH 2 CH(R)CO 2 ] (2), Cp * Ir(Cl 2)[NH 2 CH(R)CO 2 Me] (5), {(C 6 Me 6)Ru(Cl)[NH 2 CH 2 CONHCH(R)-CO 2 Me]} + Cl − (6), [Cp * Ir(Cl)NH 2 CH 2 CONCH(R)CO 2 Me] (7), [Cp * Ir(Cl)NH 2 CH(CH 2 CHMe 2)-CONCH(R)CO 2 Me)] (8), and Cp * Ir(Cl 2)[NH 2 CH 2 CONHCH(R)CO 2 Me) (9). With pentaglycine the complexes [Cp * Ir(Cl 2)(pentaglycinate + Na +)] (10) and [(C 6 Me 6)Ru(penta-glycineOMe-H +)] (11) could be isolated. Coordination of one equivalent of the S-protected tripeptide glutathione to [Cp * Ir(Cl)] and to [(C 6 Me 6)Ru(Cl)] was observed. Some in situ prepared (p-cymene)Ru complexes with deprotonated dipeptide esters were tested as catalysts and the complex [(p-cymene)Ru(Cl)(NH 2 CH(CHMeEt)NCH (CHMe 2)CO 2 tert-Bu)] gave a yield of 73% and moderate entantiomeric excess (36% ee) in the transfer hydrogenation of acetophenone to 2-propanol.