Therapeutic efficacy of linalool for the topical treatment of parasitic otitis caused by Psoroptes cuniculi in the rabbit and in the goat (original) (raw)
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Indian Journal of Animal Research, 2021
Background: The present study was conducted to evaluate the therapeutic efficacy of fipronil, ivermectin and clove oil against frequently reported Psoroptes cuniculi mites which are responsible for causing intense pruritus and scab formation on skin, ear pinna and ear canal in domestic rabbits (Oryctolagus cuniculus). Methods: The rabbits were divided into 3 groups viz. A, B and C each having 10 rabbits. These groups were topically treated with fipronil, ivermectin and clove oil on days 0, 7, 14 and 21. Pre and post treatment evaluations were made on the basis of clinical improvement and microscopic examination of skin scrapings in each group. Conclusion: Results revealed that all 3 drugs were effective against P. cuniculi; but ivermectin led recovery was quicker than rest of the two drugs. All three groups were free of lesions and mites on day 21 of treatment.
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Polish Journal of Veterinary Sciences
The ear mite “Psoroptes cuniculi” is the main cause of ear mange, a highly contagious parasitic skin disease in rabbits all over the world. In the current work, a preliminary therapeutic trial to study the effect of the broad use acaricides doramectin and ivermectin on P. cuniculi was performed on artificially infested rabbits. Twenty five adult New Zealand white rabbits were used in this study. The rabbits were assigned randomly into five groups/ 5 rabbits in each group. Each rabbit was experimentally infested with 100 mites/ ear. The first group was designated the positive control group and was not treated. The second and third groups were treated with doramectin 200 and 400 μg/kg bw, respectively. Groups 4 and 5 were treated by dressing with ivermectin in one dose and 2 doses with a 1 week interval. After the therapy, all rabbits were examined microscopically on the 7th, 14th, and 28th day post treatment and the number of live mites (larvae, nymphs, and adults) on each rabbit was...
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Revue de médecine vétérinaire
In this study, clinical and in vivo acaricidal effects of pour-on administered cypermethrin in rabbits with Psoroptes cuniculi were evaluated. Totally 24 rabbits were used in the study. Sixteen rabbits, naturally infested with P. cuniculi were randomly divided into two equal experimental groups and cypermethrin was pour-on administered 5 mg/kg (Group I) and 10 mg/kg (Group II) as a single dose. Also, 8 healthy animals (non-infested with P. cuniculi) exposed only saline were used for the control group. Psoroptic mange was diagnosed and monitored in the experimental groups by otoscopic and microscopic evaluations on Day 0 (pretreatment) and Days 1, 3, 7, 14, and 21 after the treatment. Clinical findings about psoroptic mange were scored, blood cypermethrin concentrations and haematological parameters were determined on the evaluation days. Six rabbits from Group I had P. cuniculi and a statistically important difference was determined between number of infested rabbits of Group I and ...
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Journal of Experimental and Applied Animal Sciences
In the current report, a preliminary observation to study the adverse effects of the broad use acaricides fipronil (FPN) in rabbits infested with Psoroptes cuniculi. Two separate groups (5 rabbits/each) treated topically (poured on at the base of the neck) with fipronil 5%, 1 vial/ 10 kilogram body weight (kg bw) and 1 vial/ 5 kg bw. After FPN spot on application, rabbits in both groups examined microscopically on the 7th, 14th, and 28th day post treatment and the number of live mites (larvae, nymphs, and adults) on each rabbit counted at the end of the experiment (28th day). The results showed that the number of mites in rabbits topically treated with FPN did not show significant decrease, moreover a decrease in both treated rabbits body weight (bw) and in performance observed clearly, with some attendant mortality. In conclusion, this work showed that FPN was with limited efficacy on P. cuniculi and had some undesirable side effects. Further and in-depth studies on FPN toxicity in...
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THE EFFECTIVENESS OF NEW PREPARATIONS OF NATURAL ORIGIN BY PSOROPTOSIS AND NOTOEDROSIS OF RABBITS
2017
Effective, ecologically safe methods for cleaning rabbits from the scabies Psoroptes cuniculi and Notoedres cuniculi in industrial farms and farms have been developed. It was found that after complete treatment with 4% and 8% solutions of the preparation Vita-Start, all the experimental animals, regardless of their degree of damage, recovered completely. An increase in the concentration of up to 4% and 8% in this preparation increased the lethal effect of the action on the tick of Notoedres cuniculi up to 100%. When treating animals with a slight degree of notoedrosis with a solution of Neo (5: 5) 4% and 8%, extensive efficacy was 7.5% and 52%, with an average degree of 5% and 47.6%.
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