Prevalence of Essential Tremor: A Door-to-Door Survey in Bidasoa, Spain (original) (raw)
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Prevalence of essential tremor: A door-to-door survey in Sile, Istanbul, Turkey
Parkinsonism Relat Disord, 2009
The aim of this study was to determine the prevalence of essential tremor (ET) in a Turkish population living in Şile, a rural town located on Black Sea coast of Istanbul. This study was designed as a descriptive cross-sectional field study. People aged 18 years and over were selected for the study. Tremor surveillance questionnaire was applied by door-to-door visits. Subsequently, all subjects who answered the questionnaire had a standard tremor examination. Diagnosis was made based on Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET) diagnosis and clinical evaluation scale. A total of 2227 people was screened. The prevalence of ET was found to be 3.09% (95% Cl = 2.42–3.91%) in Turkish population aged over 18 years. The prevalence of ET increased by age in both genders.
Prevalence of Tremor Disorders in Young Male Population of Turkey
2017
Objective: Prevalence studies of tremor disorders for young ages are less. The worldwide prevalence of essential tremor for all ages over 18 is approximately between 0.39% and 4.2%. The primary goal of this study is to investigate the prevalence of essential tremor and as well as prevalence of other tremor disorders in young male persons. Methods: A total of 7200 male individuals, coming from different geographic regions for attending to the army forces in a city in the west of Turkey, Çanakkale, enrolled in the study. Their ages varied between 20 and 36. The study was planned in 2 phases. In the first phase, a physician who was trained about tremor evaluation examined the participants by taking their anamnesis and physical examination. The tremors detected in this phase were re-evaluated by a neurologist in the second phase. Essential tremor was diagnosed according to the criteria of Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET), physiological tremor and psychogenic tremor were diagnosed according to the Consensus Statement of the Movement Disorder Society on Tremor. Results: The number of participants with tremor was found to be 626 (8.7%) in the first phase and they were sent to the hospital for the second phase. Examination of the participants by the neurologist, revealed essential tremor in 226 (3.13%), physiological tremor in 318 (4.41%) and psychogenic tremor in 82 (1.13%). Conclusion: Essential tremor prevalence we found in young male individuals is higher than the similar studies. Again in our study, we detected physiological tremor prevalence similar to essential tremor.
Proceedings of the Latvian Academy of Sciences. Section B. Natural, Exact, and Applied Sciences., 2015
Essential tremor (ET) is a common movement disorder, characterised by symptoms such as bilateral postural and kinetic tremor with prevalent manifestation in hands. The disease has chronic progressive development. In the case of continuous severe form it may resemble Parkinson’s disease (PD) and sometimes comorbidity with PD is possible. Although both diseases have different pathogenesis and treatment, some tremor characteristics for both are similar, thus causing difficulties and mistakes in diagnosing. The aim of the research was to determine ET characteristics within the Latvian population to identify possible causes for making mistakes.
Case-control study of patients with essential tremor in Latvia
European Journal of Neurology, 2008
Background: Essential tremor (ET) is the most prevalent inherited movement disorder. ET has been mapped on chromosomes 2 and 3, but causative genes are not known. Methods: We genotyped 16 microsatellite markers in a case-control cohort consisting of 104 patients and 116 controls. Results: No significant difference between allele frequencies was found. The highest difference of frequencies was found in allele 171 of the marker D2S220 (OR 0.13, 95% CI 0.02-1.03, P = 0.05). In addition, we investigated the distribution of suspected disease gene DRD3 Ser9Gly polymorphism in the same patients and controls. Conclusion: There was not a significant difference in genotypic distribution between disease group and control subjects (v 2 = 2.8, P = 0.25).
The prevalence of essential tremor in Edirne and its counties accompanied comorbid conditions
Neurological Research, 2019
Objective: We aimed to determine the prevalence and risk factors of Essential Tremor (ET) in Edirne and its districts, located in Western Thrace, which is the most western part of Turkey. Methods: In this study, 3008 individuals who could communicate and agreed to participate in the study were evaluated. To obtain the data from the applicants in 30 Family Health Centres in Edirne and its districts, a face-to-face questionnaire that consisted of 37 questions was prepared by the researchers. The questionnaire included general information, questions to evaluate potential concomitant comorbid conditions and questions regarding the symptomatology used in ET diagnosis, as well as questions to evaluate ET severity, was examined with the spiral test. Patients were classified by using the Washington Heights-Inwood Genetic Study of Essential Tremor (WHIGET) diagnostic and clinical evaluation scale. According to the diagnostic criteria for ET (used in participants who were examined and in those whose medical records were reviewed) were similar to those used in astudy conducted in Turkey. Results: Of 3008 individuals, 173 were diagnosed with ET according to the questionnaire results from Edirne and its districts, and the prevalence of ET was 5.8%. Approximately, 43.4% of the patients with ET were male, and 56.6% were female, which was not significantly different (p > 0.05). Participants with tremor related to alcohol withdrawal, hyperthyroidism, anxiety, depression other known causes of tremor were not considered to have ET. Thyroid disease was identified in 0.0% of the cases, and the control group was detected in 1.4%, which was not significantly different (p = 0.170). Psychiatric disease was identified in 0.0% of the cases, and the control group was detected in 1.3%, which was not significantly different (p = 0.271). Conclusions: ET prevalence studies will increase the awareness of the community and provide early diagnosis and treatment, as well as serve as a basis to reduce morbidity and improve the quality of life.
Epidemiology and Genetics of Essential Tremor
Movement Disorders, 2008
Essential tremor (ET) is one of the most common movenient disorders. Howevcr. the etiology and pathogenesis are as yet unknown. Continued research will give us clues to understanding the impact o n society. identifying genetic and environmental contributors t o the disease, understanding the significance of a sporadic case. the phenotypic spectrum and timing of presentation. and the relationship with other neurologic disorders. Because the condition is both clinically and genetically heterogeneous and there is overlap with these other disorders, such as dystonia, parkinsonism. peripheral neuropathy. and migraine, the definition of phenotype plagues research in this area. Advances in understanding the genetic and molecular underpinnings of tremor should provide additional tools to unravel the clinical phenotype (including physiology). genotype-phenotype relationships, and the epidemiology of tremor.
Prevalence of Essential Tremor in the Faroe Islands: A Population-Based Study
Neuroepidemiology
Background: No studies of the prevalence of one of the most common movement disorders, essential tremor (ET), have been undertaken in the Faroe Islands. Given the potential for founder effects in the Islands, and the highly genetic nature of ET, the Faroe Islands provide a particularly interesting setting in which to study the prevalence of ET. Objective: To estimate the prevalence of ET and study its characteristics. Methods: We used a 2-phase, population-based design, screening 1,328 randomly selected Faroese individuals aged ≥40 years. A subsample of 282 individuals who had returned the spirals and questionnaire was selected to participate in an in-person clinical evaluation. Tremor was systematically quantified by a senior movement disorder neurologist with particular specialization in tremor using a reliable and valid clinical rating scale followed by the application of rigorous diagnostic criteria used by tremor investigators internationally. Results: The overall crude prevalence was 2.9%. The age-adjusted prevalence was 3.1%. There was an age-associated rise in prevalence; by age ≥70, prevalence reached 4.8%. Twenty six of 27 (96.2%) were previously undiagnosed. Conclusions: This is the first population-based study of the prevalence of ET in the Faroe Islands. The estimated prevalence was similar to studies using the same or comparable methodologies.
Hereditary essential tremor in Buenos Aires (Argentina)
Arquivos de Neuro-Psiquiatria, 1988
A descriptive trial of essential tremor in Buenos Aires city is proposed. It may be considered as the first one like this in Latin America. During a 15 years period, sixteen families with essential tremor diagnosis have been examined, making a total of 39 patients (20 males and 19 females). The disease was basically studied from its semiological, clinico-evolutive and therapeutical view point, following a protocol. Our results indicate - a. The clinico-evolutive characteristics: its frequency (according to race, sex, social status, age of beginning and physiopathological type), morbility and mortality, evolution, prognosis, triggering factors, longevity and multiparity. b. The different treatment given to our patients with discussion of their pharmacokinetic and pharmacodynamic basis and evaluation of the best responses. In this matter, it is concluded that both primidone (750 mg/daily) and/or propranolol (160-240 mg/daily) are undeniably the drugs of first choice for the treatment ...
Clinical Characteristics of Essential Tremor in South India: A Hospital-Based Cohort Study
Journal of Neurosciences in Rural Practice, 2019
Introduction: Essential tremor (ET) is the most common adult movement disorder. Classic ET is characterized by action tremor of hands (95% cases), and tremor involving other regions is less common. Recent studies have revealed a few patients exhibiting nontremor features that include cognitive disorders, tandem gait abnormality, mood fluctuations, olfactory abnormality, hearing impairment, and sleep disorders. Very few studies on ET have so far been conducted in India, and the present study is a pioneering attempt to evaluate the clinical characteristics of patients diagnosed with ET. Materials and Methods: A standardized assessment protocol was used to collect data. Diagnosis of ET was established using consensus criteria established by the Movement Disorder Society. Tremor Research Group Essential Tremor Rating Assessment Scale was used to evaluate tremor impact. The severity of hand tremor was assessed by Glass Scale, and cognitive function was assessed by Mini-Mental Status Examination. Results: Out of the 45 patients enrolled, 73.3% were male and 26.6% were female, with a mean age of 44 ± 15 years. Postural tremor was observed in all, followed by intention tremor in 9 and rest tremor in 6 patients. Tremor of the hand was identified to be most predominant (100%). Voice tremor was observed in 15 (33.3%) patients and head tremor in 12 patients (26.6%) who were all females. Leg tremor was observed in 12 patients (26.6% of patients) and tongue tremor in 6 (13%) patients. Baseline asymmetry of tremor was observed in 60% of patients and positive family history in 35% of patients. The most common nontremor feature was tandem gait abnormality (40%). Moreover, most of the patients had Glass Scale ΙΙ. Conclusion: Baseline asymmetry of tremor and male predominance were observed in the study. While hand tremor was the most common form of tremor, tandem gait abnormality was the most common nontremor feature as observed in patients with ET.