Capillary electrochromatography: A review (original) (raw)

. Abstract: Capillary electrochromatography CEC is a modern liquid chromatographic technique which has attracted renewed curiosity from the scientific community in recent years, despite having origins in the 1970s. The growing interest in this field is reflected in the increasing number of scientific publications and presentations dealing with the technique; the majority of work reviewed here is from the last five years. This review concerns itself primarily with both the development of capillary electrochromatography, from early experimentation to the present day, and its widespread application. The fundamental theory is dis-Ž cussed, as well as experimental aspects such as mode of operation isocratic or . gradient and detection. Considerable attention is devoted to CEC columns; in particular, the preparation of frits and their associated problems. A large number of applications are summarised in tabular form, which provides an insight into the capabilities and scope of this technique.