Effect of membrane charge density on the protein corona of cationic liposomes: Interplay between cationic charge and surface area (original) (raw)

Applied Physics Letters, 2011

Abstract

Here we investigate the effect of membrane charge density on the protein corona that forms upon exposure of cationic liposomes to human plasma. We show that the protein corona around cationic liposomes is not uniquely defined by membrane charge density, but it is deeply affected by both the overall cationic charge and the available surface area. Remarkably, changes in protein

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