Use of the hydrated rat to assay diuretic and antidiuretic activity of drugs
Albert Defelice
Drug Development Research, 1991
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Effects of Drugs and Excipients on Hydration Status
Teresa Partearroyo
Nutrients
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Effects of dehydration on renal aminopeptidase activities in adult male and female rats
Marc de Gasparo
Regulatory Peptides, 2002
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Isotonic NaCl intake by cell-dehydrated rats
Daniela Pereira
Physiology & Behavior, 2002
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Intestinal drug absorption during induced net water absorption in man; a mechanistic study using antipyrine, atenolol and enalaprilat
Anna-lena Ungell
British Journal of Clinical Pharmacology, 1994
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Changes in electrolyte excretion following intraperitoneal injection of dibutyryl cyclic AMP in the brattleboro rat
G Eknoyan
Life Sciences, 1974
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Drinking Water and Drug Dosage in Rat Studies
Preben Jakobsen
Acta Pharmacologica et Toxicologica, 2009
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Effects of theophylline, choleragen and loperamide on rabbit ileal fluid and electrolyte transport in vitro
Richard Naftalin
British Journal of Pharmacology, 1987
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Impact of gastric acid suppressants on cytochrome P450 3A4 and P-glycoprotein: Consequences for FK506 assimilation
Kristin Verbeke
Kidney International, 2005
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Theophylline has no advantages over caffeine as a putative model drug for assessing CYP1A2 activity in humans
Kim Brøsen
British Journal of Clinical Pharmacology, 1997
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Prediction of Human Intestinal First-Pass Metabolism of 25 CYP3A Substrates from In Vitro Clearance and Permeability Data
brian houston
Drug Metabolism and Disposition, 2010
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Adenosine Effects on Renal Function in the Rat: Role of Sodium Intake and Cytochrome P450
Agnieszka Walkowska, Elżbieta Kompanowska-jezierska
Nephron Physiology, 2013
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Effects of chloride transport inhibitors on intestinal fluid and ion transport in vivo and in vitro
Jan Mattsson
Acta Physiologica Scandinavica, 1993
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Use of isolated kidney cells for study of drug metabolism
Kari Ormstad
Biochemical Pharmacology, 1979
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Inhibition of cell dehydration-induced drinking by tachykinins: Evaluation of possible renal effects accounting for the long-lasting inhibition
Pierluigi Pompei, Roberto Ciccocioppo
Physiology & Behavior, 1992
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Antipyrine disposition in the dehydrated camel
R. Yagil
Journal of Veterinary Pharmacology and Therapeutics, 1995
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Theophylline has no advantages over caffeine as a putative model drug for assessing CYPIA2 activity in humans
Kim Brøsen
British Journal of Clinical Pharmacology, 1997
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Effects on urine profiles of diatrizoate in hydrated and dehydrated rats
Henrik Thomsen
Acta Radiologica, 1988
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Unmasking the dynamic interplay between intestinal P-glycoprotein and CYP3A4
Carolyn Cummins
Journal of Pharmacology and …, 2002
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Inhibition of fluid transport in the isolated gall bladder of the guinea pig by isoprenaline, theophylline and cyclic adenosine 3′,5′-monophosphate
Karl_Uwe Petersen
Naunyn-schmiedebergs Archives of Pharmacology, 1974
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The effects of theophylline and choleragen on sodium and chloride ion movements within isolated rabbit ileum
Richard Naftalin
The Journal of Physiology, 1979
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A Urine Metabolic Ratio of Dextromethorphan and 3-Methoxymorphinan as a Probe for CYP3A Activity and Prediction of Cyclosporine Clearance in Healthy Volunteers
Lawrence Fleckenstein
Pharmacotherapy, 1999
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Effects of ATP on rat renal haemodynamics and excretion: role of sodium intake, nitric oxide and cytochrome P450
Agnieszka Walkowska, Elżbieta Kompanowska-jezierska
Acta Physiologica, 2007
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Tacrine is not an ideal probe drug for measuring CYP1A2 activity in vivo
Kim Brøsen
1999
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Liver carbonic anhydrase and urea synthesis the effect of diuretics
Dieter Häussinger
Biochemical Pharmacology, 1986
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An assay of the capacity of biological fluids to stimulate renal glucose-6-phosphate dehydrogenase activity in vitro as a marker of their ability to inhibit sodium potassium-dependent adenosine triphosphatase activity
Euan Clarkson
Journal of Endocrinology, 1982
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Micropuncture study of the effect of various diuretics on sodium reabsorption by the proximal tubules of the dog
J. Dirks
Journal of Clinical …, 1966
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Contribution of the Human Kidney to the Metabolic Clearance of Drugs
Tom Vree
Annals of Pharmacotherapy, 1992
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Evaluation of increased bioavailability of tacrolimus in rats with experimental renal dysfunction
Ikuko Yano, Ken-Ichi Inui
Journal of Pharmacy and Pharmacology, 2002
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Dextromethorphan to dextrorphan urinary metabolic ratio not sensitive enough to assess modest changes in CYP2D6 activity
s. borges
2004
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The Effects on Metabolic Clearance when Administering a Potent CYP3A Autoinducer with the Prototypic CYP3A Inhibitor, Ketoconazole
Stephen Lowe
Drug Metabolism and Disposition, 2012
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Inhibitory effects of calmodulin antagonists on urinary enzyme excretion in rats after nephrotoxic doses of mercuric chloride
Steadman Harrison III
Bulletin of Environmental Contamination and Toxicology, 1985
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The use of isolated enterocytes to study Phase I intestinal drug metabolism: validation with rat and pig intestine
Peggy Gandia
Fundamental & Clinical Pharmacology, 2011
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Pharmacokinetics and the effect of probenecid on the renal excretion mechanism of diprophylline
Toshitaka Nabeshima
Journal of Pharmaceutical Sciences, 1992
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Urine flow-dependence of theophylline renal clearance in man
Thomas Tozer
Journal of Pharmacokinetics and Biopharmaceutics, 1982
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