Structural and kinetic studies on ligand binding in wild-type and active-site mutants of penicillin acylase
Arjan Snijder
Protein Engineering Design and Selection, 2004
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Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism 1 1Edited by K. Nagai
George Dodson
Journal of Molecular Biology, 2001
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Crystal structures of penicillin acylase enzyme-substrate complexes: structural insights into the catalytic mechanism
Colin McVey
Journal of Molecular Biology, 2001
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Structural Studies of Penicillin Acylase
Colin McVey
Applied Biochemistry and Biotechnology, 2000
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Kinetic studies and molecular modelling attribute a crucial role in the specificity and stereoselectivity of penicillin acylase to the pair ArgA145-ArgB263
Jose Kaneti, Ivaylo Ivanov
European Journal of Biochemistry, 2004
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A Homology Model of Penicillin Acylase from Alcaligenes faecalis and In Silico Evaluation of its Selectivity
Paolo Braiuca
Chembiochem, 2003
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Structure mediation in substrate binding and post-translational processing of penicillin acylases: Information from mutant structures of K luyvera citrophila penicillin G acylase
Nishant Kumar Varshney
Protein Science, 2015
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Mutations of penicillin acylase residue B71 extend substrate specificity by decreasing steric constraints for substrate binding
M Morillas
Biochemical Journal, 2003
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Structure of a slow processing precursor penicillin acylase from Escherichia coli reveals the linker peptide blocking the active-site cleft
Garib Murshudov
Journal of Molecular Biology, 2000
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Crystallization and X-ray structure analysis of a thermostable penicillin G acylase from Alcaligenes faecalis
Asmita Prabhune
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2012
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Exploring the molecular basis of the enantioselective binding of penicillin G acylase towards a series of 2-aryloxyalkanoic acids: A docking and molecular dynamics study
Sandro Cosconati
Journal of Molecular Graphics and Modelling, 2007
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Cloning, preparation and preliminary crystallographic studies of penicillin V acylase autoproteolytic processing mutants
Asmita Prabhune
Acta Crystallographica Section F Structural Biology and Crystallization Communications, 2005
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Structure-Based Stabilization of an Enzyme: The Case of Penicillin Acylase from Alcaligenes faecalis
TIANWEN WANG
Protein and Peptide Letters, 2006
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Influence of the enzyme derivative preparation and substrate structure on the enantioselectivity of penicillin G acylase
Auro Tagliani, Massimo Pregnolato
Enzyme and Microbial Technology, 2002
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Trapping of an Acyl–Enzyme Intermediate in a Penicillin-binding Protein (PBP)-catalyzed Reaction
Alexandre Martins
Journal of Molecular Biology, 2008
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The Refined Crystallographic Structure of aDD-Peptidase Penicillin-target Enzyme at 1.6 Å Resolution
Alexandre Kuzin
Journal of Molecular Biology, 1995
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Interaction of penicillin V acylase with organic solvents:: Catalytic activity modulation on the hydrolysis of penicillin v
Miguel Arroyo
1999
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Engineering the Substrate Specificity of a Thermophilic Penicillin Acylase from Thermus thermophilus
Lorena Torres, Ana Isabel Marina Ramírez
Applied and Environmental Microbiology, 2013
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Site-directed chemical conversion of serine to cysteine in penicillin acylase from Escherichia coli ATCC 11105. Effect on conformation and catalytic activity
Janet Horrocks
European Journal of Biochemistry, 1991
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Chemical mechanism of penicillin V acylase from Streptomyces lavendulae: pH-dependence of kinetic parameters
Isabel De La Mata
Journal of Molecular Catalysis B: Enzymatic, 2001
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Cloning of penicillin acylase from Escherichia coli: Catalytic properties of recombinant enzymes
V. Tishkov
Moscow University Chemistry Bulletin, 2008
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Evidence for involvement of arginyl residue at the catalytic site of penicillin acylase from Escherichia coli
Asmita Prabhune
Biochemical and Biophysical Research Communications, 1990
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Biotechnological applications of penicillin acylases: state-of-the-art
Rawan Mnasra
Applied microbiology and …, 2003
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Stabilization of Penicillin G Acylase from Escherichia coli : Site-Directed Mutagenesis of the Protein Surface To Increase Multipoint Covalent Attachment
ramon gonzalez
Applied and Environmental Microbiology, 2004
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