Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae (original) (raw)

Multiple sites for double-strand breaks in whole meiotic chromosomes of Saccharomyces cerevisiae

1992

Drora Zenvirth

Amir Sherman

Abstract

Abstract We present a scheme for locating double-strand breaks (DSBs) in meiotic chromosomes of Saccharomyces cerevisiae, based on the separation of large DNA molecules by pulsed field gel electrophoresis. Using a rad50S mutant, in which DSBs are ...

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