P-glycoprotein and multidrug resistance (original) (raw)

Comwell MM, Gottesman MM, Pastan I: Increased vinblastine binding to membrane vesicles from multidrug resistant KB cells. I Biol Chem 1966, 262:7921-7928. Bruggemann EP, Currier SJ, Gottesman MM, Pastan I: Characterization of the azidopine and vinblastine binding site of P-glycoprotein. I Biol Chem 1992, 267:21020-21026. Ambudkar SV: Purification and reconstitution of functional human P-glycoprotein. J Bioenerg Biomembr 1995, 27:23-29. Roepe PD, Wei LY, Cruz J, Carlson D: Lower electrical membrane potential and altered pHi homeostasis in multidrugresistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein. Biochemistry 1993, 32:11042-l 1056. Weaver JL, Szabo G, Pine PS, Gottesman MM, Goldenberg S, Aszalos A: The effect of ion channel blockers, immunosuppressive agents, and other drugs on the activity of the multi-drug transporter. Int I Cancer 1993, 54:456-461. Shapiro AB, Ling V: Reconstitution of drug transport by purified P-glycoprotein. J B/o/ Chem 1995, 270:16167-l 6175. Hrycyna CA, Zhang S, Ramachandra M, Ni B, Pastan I, Gottesman MM: Functional and molecular characterization of the human multidrug transporter. In Multidrug Resistance in Cancer Cells: Cellular, Biochemical, Molecular and Biological Aspects. Edited by Gupta S, Tsuruo T. New York: John Wiley and Sons; 1996:29-37. Ramachandra M, Ambudkar SV, Pastan I, Gottesman MM, Hrycyna CA: Functional characterization of a glycine 165 to valine substitution in human P-glycoprotein using a vaccinia based transient expression system. MO/ Biol Cell 1996, in press.