Dendritic Cells Derived from Murine Colonic Mucosa Have Unique Functional and Phenotypic Characteristics (original) (raw)
2007, The Journal of Immunology
AI-generated Abstract
Dendritic cells (DCs) from the murine colonic mucosa exhibit distinct functional and phenotypic characteristics compared to those from other tissues. The study isolates colonic DCs using a magnetic labeling technique, highlighting their unique ability to process antigens, lower expression of Toll-like receptors (TLRs), yet an enhanced responsiveness to certain stimuli. This suggests that colonic DCs are specialized to respond to their specific microenvironment, with implications for understanding mucosal immunity.
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