Metabolomic Analyses of Plasma Reveals New Insights into Asphyxia and Resuscitation in Pigs (original) (raw)

Ola Saugstad

2010, PLoS ONE

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12 pages

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Background: Currently, a limited range of biochemical tests for hypoxia are in clinical use. Early diagnostic and functional biomarkers that mirror cellular metabolism and recovery during resuscitation are lacking. We hypothesized that the quantification of metabolites after hypoxia and resuscitation would enable the detection of markers of hypoxia as well as markers enabling the monitoring and evaluation of resuscitation strategies.