Randomized controlled trials in healthy volunteers Effects of Coffee Consumption on Fasting Blood Glucose and Insulin Concentrations (original) (raw)

Mougios, Vassilis, Susanne Ring, Anatoli Petridou, and Michalis G. Nikolaidis. Duration of coffee-and exercise-induced changes in the fatty acid profile of human serum. longed moderate exercise increases the concentration of nonesterified fatty acids (NEFA) and the ratio of unsaturated to saturated (U/S) NEFA in human plasma. The present study examined the duration of these effects and compared them with the effects of coffee ingestion. On separate days and in random order, seven men and six women 1) cycled for 1 h, 2) ingested coffee containing 5 mg caffeine/kg body mass, 3) ingested coffee followed by exercise 1 h later, and 4) did nothing. Blood samples were drawn at 0, 1, 2, 4, 8, 12, and 24 h. Serum was analyzed for lactate, glucose, glycerol, individual NEFA, triacylglycerols, total cholesterol, and HDL cholesterol. Exercise elevated the U/S NEFA and the percentage of oleate, while decreasing the percentages of palmitate and stearate, at the end of exercise but not subsequently. Consumption of coffee triggered a lower lipolytic response with no alterations in U/S or percentages of individual NEFA. These findings may prove useful in discovering mechanisms mediating the effects of exercise training on the fatty acid profile of human tissues. glycerol; lactate; nonesterified fatty acids; saturated fatty acids; unsaturated fatty acids Address for reprint requests and other correspondence: V. Mougios, TEFAA, Univ. of Thessaloniki,