DESIGN OF LOW POWER OPERATIONAL TRANSCONDUCTANCE AMPLIFIER FOR BIOMEDICAL APPLICATIONS (original) (raw)

An ultra-low power high gain CMOS OTA for biomedical applications

Analog Integrated Circuits and Signal Processing, 2019

An ultra-low power bulk-driven operational transconductance amplifier circuit for biomedical applications is presented. Higher DC gain and improved slew rate is achieved using double recycling technique, cross-coupled positive feedback configuration and driver transistors to enhance the transconductance of the conventional bulk-driven folded cascode amplifier. The post layout simulation of the proposed bulk-driven double recycling OTA in 180 nm CMOS technology, shows a 30 dB DC gain improvement and a 250% enhancement in GBW. The above results are validated using the Monte Carlo process variation and corner case simulations. The amplifier consumes 145 nW @ 0.6 V supply voltage.

Analysis and design of a highly linear CMOS OTA for portable biomedical applications in 90 nm CMOS

Microelectronics Journal, 2017

This paper presents the analysis and design of a new CMOS highly linear digitally programmable operational transconductance amplifier (DPOTA). The proposed DPOTA is used to design a fourth-order low pass filter for a portable Electroencephalogram (EEG), Electrocardiogram (ECG) and Electromyography (EMG) detection systems. The performance of the proposed DPOTA and the low pass filter is validated through simulation results using 90 nm CMOS technology under a balanced 1.2 V supply voltage. The transconductance value of the proposed DPOTA can be controlled, from 25 nA/V to 400 nA/V, by a 4-bit digital word. The IM3 of the proposed DPOTA is 45 dB with two single tones at frequency 60 Hz and 80 Hz and an amplitude of 20 mV p−p each. The low pass filter cutoff frequency can be adjusted to 107 Hz, 257 Hz, and 537 Hz. The third-order harmonic distortion (HD3) of the filter is 51 dB for 20 mV p−p at 100 Hz sinusoidal input signal.

HSPICE simulation and analysis of current reused operational transconductance amplifiers for biomedical applications

International Journal of Electrical and Computer Engineering (IJECE), 2025

The proposed work focuses on the design of a current-reused biomedical amplifier; it is a microwatt-level electrocardiogram (ECG) analog circuit design that addresses low power consumption and noise efficiency. As implantable devices require unobtrusiveness and longevity, the current reuse technique in this circuit effectively enhances power and noise efficiencies. Using 90 nm technology enables efficient circuit implementation, yielding promising simulation results. At 100 Hz, the noise performance reaches 62.095 nV/√Hz, while the power consumption is only 8.3797 µW. These advancements are pivotal for next-generation implantable devices, ensuring reliable operation and reducing frequent battery replacements, improving patient convenience. Moreover, the high noise efficiency ensures that ECG signals are captured with high fidelity, crucial for accurate monitoring and diagnosis. This research addresses the challenges in implantable ECG analog circuit design and sets a benchmark for future developments. The techniques employed can be adapted for other bio signal monitoring devices, broadening the impact on healthcare technology. Ultimately, this advancement contributes to more efficient, reliable, and long-lasting medical devices, enhancing patient monitoring and healthcare on a broader scale.

A HIGH CMRR, LOW-POWER OPERATIONAL TRANSCONDUCTANCE AMPLIFIER WITH 0.18μM CMOS TECHNOLOGY

IASET, 2013

This paper represent an Operational Transconductance Amplifier (OTA) which is a basic building block in many analog circuit such as in data converter’s (ADC &DAC), biquad filter design and instrumentation amplifiers. This OTA is implemented using 0.18μm CMOS technology with cadence environment and it has ±1.25v power supply with biasing current of 33nA. OTA has been simulated with virtuoso simulator and simulation results are measured. Post layout simulations for a 1 pF load capacitance shows that OTA achieves a gain bandwidth of 270 KHz at a phase margin 68.43° with 90.27 dB DC gain. This OTA is having CMRR of 154 dB, PSRR of 119 dB, Power dissipation of 29.58nW and Slew Rate 2.49 V/μsec.

Designing an Inverter-based Operational Transconductance Amplifier-capacitor Filter with Low Power Consumption for Biomedical Applications

Journal of Medical Signals & Sensors, 2018

The operational transconductance amplifi er-capacitor (OTA-C) fi lter is one of the best structures for implementing continuous-time fi lters. It is particularly important to design a universal OTA-C fi lter capable of generating the desired fi lter response via a single structure, thus reducing the fi lter circuit power consumption as well as noise and the occupied space on the electronic chip. In this study, an inverter-based universal OTA-C fi lter with very low power consumption and acceptable noise was designed with applications in bioelectric and biomedical equipment for recording biomedical signals. The very low power consumption of the proposed fi lter was achieved through introducing bias in subthreshold MOSFET transistors. The proposed fi lter is also capable of simultaneously receiving favorable low-, band-, and high-pass fi lter responses. The performance of the proposed fi lter was simulated and analyzed via HSPICE software (level 49) and 180 nm complementary metal-oxide-semiconductor technology. The rate of power consumption and noise obtained from simulations are 7.1 nW and 10.18 nA, respectively, so this fi lter has reduced noise as well as power consumption. The proposed universal OTA-C fi lter was designed based on the minimum number of transconductance blocks and an inverter circuit by three transconductance blocks (OTA).

A 21nW CMOS Operational amplifier for Biomedical Application

In this paper CMOS operational amplifier using a two stage has been enunciated for low power device application by using it in subthreshold region. The proposed Op amp shows high gain as well as moderate UGB using capacitor compensation technique circuit. It is operated on rail to rail power supply of ±500mV. This amplifier is highly useful for biomedical application due to low power consumption. The designed operational amplifier gain is 48dB, bandwidth is 29 KHz and phase margin is 61O, and slew rate is 50.6V/µS with 21 nW power consumption. This circuit is designed using Cadence analog & digital system design tools of UMC 90nm CMOS technology.

Low Noise Low Power CMOS Telescopic-OTA for Bio-Medical Applications

Computers, 2016

The preamplifier block is crucial in bio-medical signal processing. The power intensive Operational Transconductance Amplifier (OTA) is considered, and the performance of preamplifier is studied. A low noise and low power telescopic OTA is proposed in this work. To reduce the noise contribution in the active load transistors, source degeneration technique is incorporated in the current stealing branch of the OTA. The OTA design optimization is achieved by g m /I d methodology, which helps to determine the device geometrical parameters (W/L ratio). The proposed design was implemented in CMOS 90 nm with bias current and supply voltage of 1.6 µA and 1.2 V, respectively. The post layout simulation results of the proposed amplifier gave a gain of 62 dB with phase margin 57°, CMRR 78 dB, input referred noise 3.2 µVrms, Noise Efficiency Factor (NEF) 1.86 and power consumption of 1.92 µW.

A 0.8 V CMOS OTA and Its Application in Realizing a Neural Recording Amplifier

Journal of Medical and Bioengineering, 2015

This work presents a low-voltage, low power CMOS symmetrical operational transconductance amplifier (OTA) and its application for realization of a biopotential amplifier in neural recording application. The linear range of OTA is increased by employing multi-tanh differential configuration and source degeneration while the commonmode range is enhanced using DC-shifting scheme. The proposed symmetrical OTA is operated with a single power supply of 0.8 V and shows an open loop gain of 31.6 dB with unit gain bandwidth of 202.3 KHz and using a 7 pF of load capacitor. A neural preamplifier was implemented in moderate inversion region using the proposed OTA. The preamplifier achieves 34.5 dB of gain consuming 77.1 µW of power and has an input referred noise of 24.18 µV rms over 8.9 KHz of bandwidth. Index Terms-multi-tanh differential pair, low-voltage operational transconductance amplifier, neural preamplifier and moderate inversion