CA125 and immunoinflammatory activity in acute heart failure (original) (raw)

This study investigates the role of carbohydrate antigen 125 (CA125) as a predictor of mortality and heart transplantation in patients with acute heart failure (HF). Findings indicate that elevated CA125 levels are correlated with indicators of fluid congestion and inflammatory markers, suggesting its potential involvement in pathogenic processes beyond mere fluid overload. Furthermore, the research highlights the contribution of venous congestion in triggering inflammatory and hemodynamic pathways, which are crucial for understanding the progression of acute HF.