Evaluation of the Potential Role of Cytokines in Toxic Epidermal Necrolysis (original) (raw)

Journal of Investigative Dermatology, 2004

Abstract

Toxic epidermal necrolysis is a rare disease observed as a consequence of adverse reactions to drugs. It results in the widespread apoptosis of epidermal cells and has a high mortality rate. The mechanisms leading to this apoptosis are not yet elucidated. We investigated whether the cytokines present in the blister fluid, which accumulates under necrotic epidermis, originated from T lymphocytes

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