Direct Production of Reactive Oxygen Species from Aggregating Proteins and Peptides Implicated in the Pathogenesis of Neurodegenerative Diseases (original ) (raw )The direct production of reactive oxygen species from aggregating proteins plays a central role in the pathogenesis of several different neurodegenerative diseases
Omar El-agnaf
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Interaction of Oxidative Stress and Misfolded Proteins in the Mechanism of Neurodegeneration
Andrey Dunaev
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Protein aggregation, metals and oxidative stress in neurodegenerative diseases
David Allsop , Omar El-agnaf
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Protein Targets of Oxidative Damage in Human Neurodegenerative Diseases with Abnormal Protein Aggregates
Anna Martinez
Brain Pathology, 2010
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Formation of hydrogen peroxide and hydroxyl radicals from Aβ and α-synuclein as a possible mechanism of cell death in Alzheimer’s disease and Parkinson’s disease1,2 1This article is part of a series of reviews on “Causes and Consequences of Oxidative Stress in Alzheimer’s Disease.” The full list ...
Omar El-agnaf
Free Radical Biology and Medicine, 2002
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Reactive Oxygen Species in Neurodegenerative Diseases: Implications in Pathogenesis and Treatment Strategies
OYEDOTUN OYELEKE
Reactive Oxygen Species [Working Title]
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Protection from the Pathogenesis of Neurodegenerative Disorders, including Alzheimer's Disease, Amyotrophic Lateral Sclerosis, Huntington's Disease, and Parkinson's Diseases, through the Mitigation of Reactive Oxygen Species
Samskruthi Madireddy
Journal of Neuroscience and Neurological Disorders, 2019
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molecules Oxidative Stress: A Key Modulator in Neurodegenerative Diseases
Anju Singh
Molecules, 2019
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[Oxidative stress in neurodegeneration]
Orlando Castellano
Revista de neurologia
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Chemistry and Biochemistry of Oxidative Stress In Neurodegenerative Disease
George Perry
Current Medicinal Chemistry, 2001
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Mechanisms of protein toxicity in neurodegenerative diseases
Chang Geon Chung
Cellular and Molecular Life Sciences, 2018
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Are oxidative stress and mitochondrial dysfunction the key players in the neurodegenerative diseases?
Domenico Nuzzo , Pier Luigi San Biagio
Free Radical Research, 2012
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Protein aggregation and degradation mechanisms in neurodegenerative diseases
Annakaisa Haapasalo
American Journal of Neurodegenerative Disease, 2013
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Neurodegenerative aspects of protein aggregation
Danek Elbaum
Acta neurobiologiae experimentalis, 2004
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Oxidative Stress in Age-Related Neurodegenerative Diseases: An Overview of Recent Tools and Findings
Teresa Rubio
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Reductive stress promotes protein aggregation and impairs neurogenesis
Thomas van Groen
Redox Biology, 2020
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Neuronal response in Alzheimer's and Parkinson's disease: the effect of toxic proteins on intracellular pathways
IRHD Journal
BMC neuroscience, 2015
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Apoptotic Neuronal Cell Death Induced by the Non-fibrillar Amyloid-beta Peptide Proceeds through an Early Reactive Oxygen Species-dependent Cytoskeleton Perturbation
Christophe Klein
Journal of Biological Chemistry, 2002
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Pyruvate protection against ?-amyloid-induced neuronal death: Role of mitochondrial redox state
Milagros Ramos
Journal of Neuroscience Research, 2003
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Neurodegenerative Diseases: New Concepts of Pathogenesis and Their Therapeutic Implications
Laura Texco
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All Roads Lead to Rome: Different Molecular Players Converge to Common Toxic Pathways in Neurodegeneration
Leenor Alfahel , Adrian Israelson
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PrP is a central player in toxicity mediated by soluble aggregates of neurodegeneration-causing proteins
Dominic Walsh
Acta Neuropathologica
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Reactive oxygen species and Alzheimer's disease
Thomas Ruppert , Colin Masters
Biochemical Pharmacology, 1997
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Neurodegenerative Diseases: Parkinson’s and Alzheimer’s Diseases
Mikhail Kogan
Oxford Medicine Online, 2018
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Oxidative Stress, Mitochondrial Abnormalities and Proteins Deposition: Multitarget Approaches in Alzheimer's Disease
Simona Rapposelli
Current topics in medicinal chemistry, 2017
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Protein Conformational Pathology in Alzheimers and Other Neurodegenerative Diseases; New Targets for Therapy
Eva Zerovnik
Current Alzheimer Research, 2010
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Promotion of transition metal-induced reactive oxygen species formation by β-amyloid
Stephen C Bondy
Brain Research, 1998
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Oxidative stress induces macroautophagy of amyloid β-protein and ensuing apoptosis
Alexei Terman
Free Radical Biology and Medicine, 2009
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Review on various factors responsible for neurodegenerative disorders
Rasika Patil
GSC Biological and Pharmaceutical Sciences, 2021
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Removing Protein Aggregates: The Role of Proteolysis in Neurodegeneration
Line Kimpe
Current Medicinal Chemistry, 2011
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Pyruvate protection against β-amyloid-induced neuronal death: Role of mitochondrial redox state
Milagros Ramos
Journal of Neuroscience Research, 2003
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Amyloidogenic Proteins, in Their Fibrillar States, May Be Detrimental Via Different Mechanisms: Perspective of Po-Tential Curative/Preventive Strategies Against Neurodege-Nerative Disorders
Kamran Mansouri
Journal of Reports in Pharmaceutical Sciences, 2012
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What is the role of protein aggregation in neurodegeneration?
Michelle Poirier
Nature Reviews Molecular Cell Biology, 2005
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Editorial: Protein misfolding, altered mechanisms and neurodegeneration
Neha Gogia
Frontiers in Molecular Neuroscience
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