Expansion of Protective CD8+ T-Cell Responses Driven by Recombinant Cytomegaloviruses (original) (raw)

CD4+ T Cell Help Has an Epitope-Dependent Impact on CD8+ T Cell Memory Inflation during Murine Cytomegalovirus Infection

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Subdominant CD8 T-Cell Epitopes Account for Protection against Cytomegalovirus Independent of Immunodomination

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Epitope-specific in vivo protection against cytomegalovirus disease by CD8 T cells in the murine model of preemptive immunotherapy

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Immune control in the absence of immunodominant epitopes: implications for immunotherapy of cytomegalovirus infection with antiviral CD8 T cells

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Medical Microbiology and Immunology, 2012

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CD8-positive T lymphocytes specific for murine cytomegalovirus immediate-early antigens mediate protective immunity

Ulrich Koszinowski

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CD8 T Cells Control Cytomegalovirus Latency by Epitope-Specific Sensing of Transcriptional Reactivation

Matthias Reddehase

Journal of Virology, 2006

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Mucosal CD8+ T cell responses induced by an MCMV based vaccine vector confer protection against influenza challenge

Thomas Ebensen

2018

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In vivo impact of cytomegalovirus evasion of CD8 T-cell immunity: Facts and thoughts based on murine models

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Broadly targeted human cytomegalovirus-specific CD4+ and CD8+ T cells dominate the memory compartments of exposed subjects

Andrew Sylwester

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Proliferation Requirements of Cytomegalovirus-Specific, Effector-Type Human CD8+ T Cells

Ester Remmerswaal

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Differentiation of cytomegalovirus-specific CD8+ T cells in healthy and immunosuppressed virus carriers

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Repertoire, diversity, and differentiation of specific CD8 T cells are associated with immune protection against human cytomegalovirus disease

Christine Katlama

2000

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T-bet:Eomes balance, effector function, and proliferation of cytomegalovirus-specific CD8+ T cells during primary infection differentiates the capacity for durable immune control.

Iulia Popescu

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Molecular profiling of cytomegalovirus-induced human CD8+ T cell differentiation

Ester Remmerswaal

Journal of Clinical Investigation, 2010

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Superior induction and maintenance of protective CD8 T cells in mice infected with mouse cytomegalovirus vector expressing RAE-1

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Proceedings of the National Academy of Sciences, 2013

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CMV-specific T cells generated from naïve T cells recognize atypical epitopes and may be protective in vivo

Caridad Martinez, Patrick Hanley

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Viral Interference with Antigen Presentation Does Not Alter Acute or Chronic CD8 T Cell Immunodominance in Murine Cytomegalovirus Infection

AMELIA CRISTINA PINTO

The Journal of Immunology, 2007

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B7-Mediated Costimulation of CD4 T Cells Constrains Cytomegalovirus Persistence

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Antigen-presenting cells of haematopoietic origin prime cytomegalovirus-specific CD8 T-cells but are not sufficient for driving memory inflation during viral latency

R. Holtappels

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Immune Control Differentiates the Capacity for Durable T Cells during Primary Infection + CD8 Proliferation of Cytomegalovirus-Specific T-bet:Eomes Balance, Effector Function, and Downloaded from

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Dominance of Virus-Specific CD8 T Cells in Human Primary Cytomegalovirus Infection

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Persistent viral infection in humans can drive high frequency low-affinity T-cell expansions

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Suppression of CD8+ T-cell recognition in the immediate-early phase of human cytomegalovirus infection

Andreas Moosmann

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Highly Protective In Vivo Function of Cytomegalovirus IE1 Epitope-Specific Memory CD8 T Cells Purified by T-Cell Receptor-Based Cell Sorting

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Journal of Virology, 2005

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Response Memory Phenotype of the CD8 T Cell Effect on the Size or the Effector with Antigen Presentation Has Little Murine Cytomegalovirus Interference

Ulrich Koszinowski

2000

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Continuous recruitment of naive T cells contributes to heterogeneity of antiviral CD8 T cells during persistent infection

David Masopust

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The Context of Gene Expression Defines the Immunodominance Hierarchy of Cytomegalovirus Antigens

Zsolt Ruzsics

The Journal of Immunology, 2013

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CD8 T Cell Vaccines and a Cytomegalovirus-Based Vector Approach

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Efficacious control of cytomegalovirus infection after long-term depletion of CD8+ T lymphocytes

Ulrich Koszinowski

Journal of virology, 1990

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Preemptive CD8 T-cell immunotherapy of acute cytomegalovirus infection prevents lethal disease, limits the burden of latent viral genomes, and reduces the risk of virus recurrence

Matthias Reddehase

Journal of virology, 1998

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Fibroblast-adapted human CMV vaccines elicit predominantly conventional CD8 T cell responses in humans

Ilias Doxiadis

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In Vitro Human Memory CD8 T Cell Expansion in Response to Cytomegalovirus Requires CD4 + T Cell Help

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