A Peptide-based Vector for Efficient Gene Transfer In Vitro and In Vivo (original) (raw)

This study presents the development of a new peptide-based vector, stearyl-transportan 10 (TP10), aimed at enhancing the efficiency of gene transfer both in vitro and in vivo. The vector leverages the unique properties of cell-penetrating peptides to facilitate the delivery of plasmid DNA, overcoming common barriers associated with traditional delivery methods. Results indicate significant improvements in transfection efficiency and cellular uptake, providing a potential alternative to viral vectors in gene therapy applications.