Serum Free Light Chain Ratio, Total  /  Ratio, and Immunofixation Results Are Not Prognostic Factors after Stem Cell Transplantation for Newly Diagnosed Multiple Myeloma (original) (raw)

AI-generated Abstract

This study investigates the prognostic significance of serum free light chain (sFLC) ratio, total light chain ratio, and immunofixation results in patients with newly diagnosed multiple myeloma (MM) post-stem cell transplantation (SCT). Among 203 patients analyzed, traditional paraprotein parameters did not correlate with overall survival (OS), while only a normal kappa/lambda ratio (KLR) was associated with extended event-free survival (EFS). These findings challenge previous assumptions about the prognostic value of sFLC in this clinical setting, indicating that achieving complete response does not significantly influence patient survival.