THE EFFECTS OF DIETARY n-6/n-3 RATIO OF POLYUNSATURATED FATTY ACIDS ON THE PHYSICAL PARAMETERS OF FEMUR AND BIOMARKERS OF BONE METABOLISM IN RATS (original) (raw)

The aim of this study was to investigate the effects of different n-6/n-3 fatty acid ratios in diets on body weight, physical characteristics of bones and plasma biomarkers in rats. Corn oil and flax oil were used as sources of n-6 and n-3 fatty acids, respectively, and by adding different ratios of corn and flax to a basal diet. Twenty Vistar male rats (25 days old) were randomly assigned to four dietary treatments included: treatment 1: basal diet + 5 g flax oil + 2 g corn oil; treatment 2: basaldiet + 5 g corn oil+ 2 g flax oil; and treatment 4: basal diet+ 7 g flax oil. Results showed non-significant effects of n-6 and n-3 or their combination on body weight of rats. The diameter of femur bones was significantly higher in treatment 1 than other treatments. The effect of treatments on length of femur bones was not significant (p<0.05). For calcium content of femur bones, the significant differences were found between treatments. While the dietary n-6 and n-3 fatty acid had no ...