Effect of a high-protein, energy-restricted diet on weight loss and energy expenditure after weight stabilization in hyperinsulinemic subjects (original) (raw)

2003, International Journal of Obesity

Background: It is not clear whether varying the protein-tocarbohydrate ratio of weight-loss diets benefits body composition or metabolism. Objective: The objective was to compare the effects of 2 weightloss diets differing in protein-to-carbohydrate ratio on body composition, glucose and lipid metabolism, and markers of bone turnover. Design: A parallel design included either a high-protein diet of meat, poultry, and dairy foods (HP diet: 27 % of energy as protein, 44% as carbohydrate, and 29 % as fat) or a standard-protein diet low in those foods (SP diet: 16 % of energy as protein, 57 % as carbohydrate" and 27 % as fat) during 12 wk of energy restriction (6-6.3 MJ/d) and 4 wk of energy balance (=8.2 MJ/d). Fiftyseven overweight volunteers with fasting insulin concentrations > 12 mUlL completed the study.

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