Heparin induced thrombocytopenia: prevalence in India (original) (raw)

To the Editor: Antiphospholip antibody syndrome (APLS) is characterized clinically by venous and arterial thrombosis, recurrent fetal losses and livedo reticularis, and biologically by the presence of antiphospholipid antibodies revealed by lupus anticoagulant, anticardiolipin antibodies, or less frequently by positive serology for syphilis. Antiphospholipid antibodies can interact with the platelet membrane, resulting in thrombocytopenia in about 25% of cases. Given the frequency of arterial thromboses, aspirin often is indicated.