-Catenin (CTNNB1) in the Mouse Uterus During Decidualization and the Potential Role of Two Pathways in Regulating Its Degradation (original) (raw)
This study investigates the role of beta-catenin (CTNNB1) in the mouse uterus during the process of decidualization, a critical phase for successful implantation. It highlights the significance of CTNNB1 in maintaining tissue architecture through its interaction with cadherins and its function as a transcriptional regulator. The research also explores the changes in CTNNB1's localization and activity during implantation and decidualization, suggesting that its degradation is potentially regulated by two different pathways, thus providing a deeper understanding of the molecular mechanisms underlying uterine functions.