Diagnostic relevance of ADAMTS13 activity: Evaluation of 28 patients with thrombotic thrombocytopenic purpura - hemolytic uremic syndrome clinical diagnosis (original) (raw)

This study examines the diagnostic relevance of ADAMTS13 activity in 28 patients diagnosed with thrombotic thrombocytopenic purpura (TTP) and hemolytic uremic syndrome (HUS). It highlights the significant correlations between reduced ADAMTS13 activity and TTP diagnosis, as well as links to hematological parameters such as platelet counts and lactate dehydrogenase levels. The findings underscore the importance of ADAMTS13 as a biomarker for clinical assessment in TTP and HUS, suggesting it could aid in distinguishing between idiopathic and secondary forms of TTP.