Effect of resistance exercise on postprandial lipemia (original) (raw)
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Effect of Intensity of Resistance Exercise on Postprandial Lipemia: 757
Medicine and Science in Sports and Exercise, 2008
Singhal A, Trilk JL, Jenkins NT, Bigelman KA, Cureton KJ. Effect of intensity of resistance exercise on postprandial lipemia. The purpose of this study is to determine whether moderate-intensity resistance exercise (MOD) lowers postprandial lipemia (PPL) as much as high-intensity resistance exercise (HI) of equal work. Ten healthy men performed three trials, each conducted over 2 days. On day 1 of each treatment, they either did not exercise (CON), performed 3 sets of 16 repetitions of 10 exercises at 50% of 8 repetitions maximum (MOD), or performed 3 sets of 8 repetitions of 10 exercises at 100% of 8 repetitions maximum (HI). On the morning of day 2 at 15.5 h postexercise, participants ate a high-fat meal. Venous blood samples were collected, and metabolic rate was measured at rest and 3 h postprandial. HI reduced fasting triglyceride (TG) and TG area under the curve (AUC) (36%, P ϭ 0.011 and 35%, P ϭ 0.014) compared with CON. MOD tended to reduce fasting TG and TG AUC (21%, P ϭ 0.054 and 26%, P ϭ 0.052) compared with CON, but MOD and HI did not differ in fasting TG or TG AUC. Incremental TG AUC did not differ among treatments. MOD and HI did not change resting metabolic rate. HI increased fat oxidation at rest (21%, P ϭ 0.021) and at 3 h postprandial (39%, P ϭ 0.009) relative to CON. MOD tended to increase fat oxidation at rest (18%, P ϭ 0.060) relative to CON. Fat oxidation and metabolic rate did not differ in MOD and HI. MOD and HI increased the fasting quantitative insulin-sensitivity check index (4%, P ϭ 0.001 and P ϭ 0.004) relative to CON. As MOD and HI resulted in similar reductions in PPL and increases in fat oxidation, resistance exercise intensity does not influence PPL. fat metabolism; insulin sensitivity; triglycerides; weight lifting Address for reprint requests and other correspondence: A. Singhal,
Effect of intensity of resistance exercise on postprandial lipemia
Journal of Applied Physiology, 2009
Singhal A, Trilk JL, Jenkins NT, Bigelman KA, Cureton KJ. Effect of intensity of resistance exercise on postprandial lipemia. The purpose of this study is to determine whether moderate-intensity resistance exercise (MOD) lowers postprandial lipemia (PPL) as much as high-intensity resistance exercise (HI) of equal work. Ten healthy men performed three trials, each conducted over 2 days. On day 1 of each treatment, they either did not exercise (CON), performed 3 sets of 16 repetitions of 10 exercises at 50% of 8 repetitions maximum (MOD), or performed 3 sets of 8 repetitions of 10 exercises at 100% of 8 repetitions maximum (HI). On the morning of day 2 at 15.5 h postexercise, participants ate a high-fat meal. Venous blood samples were collected, and metabolic rate was measured at rest and 3 h postprandial. HI reduced fasting triglyceride (TG) and TG area under the curve (AUC) (36%, P ϭ 0.011 and 35%, P ϭ 0.014) compared with CON. MOD tended to reduce fasting TG and TG AUC (21%, P ϭ 0.054 and 26%, P ϭ 0.052) compared with CON, but MOD and HI did not differ in fasting TG or TG AUC. Incremental TG AUC did not differ among treatments. MOD and HI did not change resting metabolic rate. HI increased fat oxidation at rest (21%, P ϭ 0.021) and at 3 h postprandial (39%, P ϭ 0.009) relative to CON. MOD tended to increase fat oxidation at rest (18%, P ϭ 0.060) relative to CON. Fat oxidation and metabolic rate did not differ in MOD and HI. MOD and HI increased the fasting quantitative insulin-sensitivity check index (4%, P ϭ 0.001 and P ϭ 0.004) relative to CON. As MOD and HI resulted in similar reductions in PPL and increases in fat oxidation, resistance exercise intensity does not influence PPL. fat metabolism; insulin sensitivity; triglycerides; weight lifting Address for reprint requests and other correspondence: A. Singhal,
Effects of low- and high-volume resistance exercise on postprandial lipaemia
British Journal of Nutrition, 2007
Postprandial lipaemia (PL) is associated with the metabolic syndrome, CVD and endothelial dysfunction. Aerobic exercise has been shown to reduce PL. Although resistance exercise is recommended for the improvement of the quality of life, management of body weight and prevention of several disorders, its effect on PL has received little attention. The present study examined the effects of low-volume resistance exercise (LVRE) and high-volume resistance exercise (HVRE) on PL. Ten healthy young men performed three trials, each conducted over 2 d. On the afternoon of day 1, they either refrained from exercise (control), performed LVRE (two sets of eight exercises, twelve repetitions at twelve repetitions maximum (RM) in each set; energy expenditure 0·76 MJ), or performed HVRE (four sets of eight exercises, twelve repetitions at 12RM in each set; energy expenditure 1·40 MJ). On the morning of day 2 they consumed a meal containing 67 kJ/kg body weight, of which 65 % energy was from fat. Blood samples were obtained in the fasted state and for 6 h postprandially. The total area under the TAG curve (AUC; mmol/l £ h) was lower (P,0·05) in HVRE (8·76 (SD 3·20)) and LVRE (9·29 (SD 3·64)) compared with control (11·60 (SD 4·35)). The incremental AUC was lower in HVRE compared with control (3·07 (SD 2·53) v. 5·58 (SD 3·72)), but not different between LVRE (3·86 (SD 2·29)) and control. In conclusion, resistance exercise of 1·40 MJ (four sets -eight exercises -twelve RM) or 0·76 MJ (two sets -eight exercises -twelve RM) before a highfat meal reduces the total postprandial lipaemic response.
Resistance exercise at variable volume does not reduce postprandial lipemia in postmenopausal women
AGE, 2014
The aim of this study was to investigate the acute effects of resistance exercise sessions (RESs) performed at different levels of high-volume resistance exercise (HVRE) and low-volume resistance exercise (LVRE) on postprandial lipemia (PPL) in postmenopausal women. Thirty-nine healthy unconditioned postmenopausal women (59.5±4.8 years of age, body mass 69.6 ± 9.1 kg, height 157.9 ± 7.2 cm, BMI 27.6 ± 4.1 kg m −2 , waist circumference 76.1±9.7 cm, VO 2max 18.7±1.4 mL kg −1 min −1 ) were assigned to a LVRE (n= 12), HVRE (n=14), and control group (CG, n=13). Experimental groups performed one RES involving eight exercises. The HVRE group performed three sets with a maximum of 15 repetitions, and the LVRE group performed one set with a maximum of 15 repetitions. Approximately 16 h after a RES, all of the groups were given an oral fat tolerance test (OFTT). During the RES, we evaluated the energy expenditure (EE) of the resistance session and excess postexercise oxygen consumption (EPOC); following the RES and the OFTT, we evaluated lipid profiles (total cholesterol, HDL, LDL, and triglycerides). While the study groups did not demonstrate significant differences in lipid profiles, the total energy expenditure (EE+EPOC) of the session exercise treatments was significantly higher for HVRE than for LVRE (0.60±0.12 and 0.31±0.11 MJ, respectively, p<0.001). Different levels of resistance exercise do not lower basal triglyceride concentration and postprandial lipid profile parameters at approximately 16 h following resistance exercise in untrained postmenopausal women.
Effect of exercise on postprandial lipemia in men with hypertriglyceridemia
European Journal of Applied Physiology, 2006
We examined the eVect of exercise on postprandial lipemia (PPL) and insulin resistance in individuals with metabolic syndrome. Subjects were 10 hypertriglyceridemia (HTG) males with insulin resistance [age = 40.1 § 2.2 years, body weight = 96.3 § 3.3 kg, fasting triglyceride (TG) = 263 § 25 mg/dl, VO 2 max = 37 § 1.1 ml/kg/min, and Homeostatic Model Assessment (HOMA-IR, an index of insulin resistance) = 3.05 § 0.40]. Each subject performed a control trial (Ctr, no exercise), and three exercise trials at 40% (40%T), 60% (60%T), and 70% (70%T) of their VO 2 max. The order of trials was randomized and there were 1-2 weeks wash-out period between the trials. All subjects had a fat-meal in each trial. In the exercise trials, subjects jogged on a treadmill for 1 h at a designated intensity 12 h prior to a fat-meal ingestion. Blood samples were taken at 0 h (before the meal), and 2, 4, 6, and 8 h after the meal. The plasma TG, area score under TG concentration curve for over an 8 h-period (TG AUC) after the meal, and HOMA-IR were analyzed. The TG AUC score in 40%T was 30% lower (P = 0.003), 60%T was 31% lower (P = 0.02), and 70%T was 39% lower (P = 0.02) than Ctr. There were no signiWcant diVerences in the TG AUC scores among the exercise trials (P > 0.05). The insulin concentrations in both 60 and 70%T were lower than Ctr (P < 0.01) which did not diVer from 40%T. HOMA-IR in both 60%T (P = 0.041) and 70%T (P = 0.002) were lower than Ctr, but not diVerent from 40%T (HOMA-IR: Ctr = 3.05 § 0.40, 40%T = 2.67 § 0.35, 60%T = 2.49 § 0.31, 70%T = 2.21 § 0.27). The results suggest that for physically inactive individuals with metabolic syndrome, exercising at low to moderate intensity may be suYcient to attenuate PPL and increase insulin sensitivity, whereas higher intensity exercise may be needed to normalize blood glucose.
Diabetologia
Aims/hypothesis Prediabetes is associated with postprandial hypertriacylglycerolaemia. Resistance exercise acutely lowers postprandial plasma triacylglycerol (TG); however, the changes in lipid metabolism that mediate this reduction are poorly understood. The aim of this study was to identify the constitutive metabolic mechanisms underlying the changes in postprandial lipid metabolism after resistance exercise in obese men with prediabetes. Methods We evaluated the effect of a single bout of whole-body resistance exercise (seven exercises, three sets, 10-12 repetitions at 80% of one-repetition maximum) on postprandial lipid metabolism in ten middle-aged (50 ± 9 years), overweight/obese (BMI: 33 ± 3 kg/m 2), sedentary men with prediabetes (HbA 1c >38 but <48 mmol/mol [>5.7% but <6.5%]), or fasting plasma glucose >5.6 mmol/l but <7.0 mmol/l or 2 h OGTT glucose >7.8 mmol/l but <11.1 mmol/l). We used a randomised, crossover design with a triple-tracer mixed meal test (ingested [(13 C 4) 3 ]tripalmitin, i.v. [U-13 C 16 ]palmitate and [ 2 H 5 ]glycerol) to evaluate chylomicron-TG and total triacylglycerol-rich lipoprotein (TRL)-TG kinetics. We used adipose tissue and skeletal muscle biopsies to evaluate the expression of genes regulating lipolysis and lipid oxidation, skeletal muscle respirometry to evaluate oxidative capacity, and indirect calorimetry to assess whole-body lipid oxidation. Results The single bout of resistance exercise reduced the lipaemic response to a mixed meal in obese men with prediabetes without changing chylomicron-TG or TRL-TG fractional clearance rates. However, resistance exercise reduced endogenous and meal-derived fatty acid incorporation into chylomicron-TG and TRL-TG. Resistance exercise also increased whole-body lipid oxidation, skeletal muscle mitochondrial respiration, oxidative gene expression in skeletal muscle, and the expression of key lipolysis genes in adipose tissue. Conclusions/interpretation A single bout of resistance exercise improves postprandial lipid metabolism in obese men with prediabetes, which may mitigate the risk for cardiovascular disease and type 2 diabetes.
High-volume resistance training reduces postprandial lipaemia in postmenopausal women
Journal of Sports Sciences, 2015
The aim of this study was to investigate the acute effects of resistance exercise sessions (RESs) performed at different levels of high-volume resistance exercise (HVRE) and low-volume resistance exercise (LVRE) on postprandial lipemia (PPL) in postmenopausal women. Thirty-nine healthy unconditioned postmenopausal women (59.5±4.8 years of age, body mass 69.6 ± 9.1 kg, height 157.9 ± 7.2 cm, BMI 27.6 ± 4.1 kg m −2 , waist circumference 76.1±9.7 cm, VO 2max 18.7±1.4 mL kg −1 min −1 ) were assigned to a LVRE (n= 12), HVRE (n=14), and control group (CG, n=13). Experimental groups performed one RES involving eight exercises. The HVRE group performed three sets with a maximum of 15 repetitions, and the LVRE group performed one set with a maximum of 15 repetitions. Approximately 16 h after a RES, all of the groups were given an oral fat tolerance test (OFTT). During the RES, we evaluated the energy expenditure (EE) of the resistance session and excess postexercise oxygen consumption (EPOC); following the RES and the OFTT, we evaluated lipid profiles (total cholesterol, HDL, LDL, and triglycerides). While the study groups did not demonstrate significant differences in lipid profiles, the total energy expenditure (EE+EPOC) of the session exercise treatments was significantly higher for HVRE than for LVRE (0.60±0.12 and 0.31±0.11 MJ, respectively, p<0.001). Different levels of resistance exercise do not lower basal triglyceride concentration and postprandial lipid profile parameters at approximately 16 h following resistance exercise in untrained postmenopausal women.
Postprandial lipemia in young men and women of contrasting training status
Journal of applied physiology (Bethesda, Md. : 1985), 2000
This study compared the postprandial triacylglycerol (TAG) response to a high-fat meal in trained and untrained normolipidemic young adults after 2 days' abstinence from exercise. Fifty-three subjects (11 endurance-trained men, 9 endurance-trained women, 10 sprint/strength-trained men, 11 untrained men, 11 untrained women) consumed a meal (1.2 g fat, 1.1 g carbohydrate, 66 kJ per kg body mass) after a 12-h fast. Venous blood samples were obtained in the fasted state and at intervals until 6 h. Postprandial responses were the areas under the plasma or serum concentration-vs.-time curves. Neither fasting TAG concentrations nor the postprandial TAG response differed between trained and untrained subjects. The insulinemic response was 29% lower in endurance-trained men than in untrained men [mean difference -37.4 (95% confidence interval -62.9 to -22.9) microIU/ml x h, P = 0.01]. Responses of plasma glucose, serum insulin, and plasma nonesterified fatty acids were all lower for endu...
Journal of Applied Physiology, 2003
This study was designed to assess differences in the intensity of exercise to attenuate postprandial lipemia (PPL). Thirteen healthy men (age 23.8 ± 0.9 yr) participated in three random-ordered trials: in low-(25% peak oxygen consumption; Low) and moderate-intensity (65% peak oxygen consumption; Mod) exercise trials, which were completed 1 h before a high-fat meal (1.3 g fat/kg body mass), and a control (Con), fat meal only, trial. Venous blood samples were obtained before the fat meal, and at 2, 4, 6, 8, and 20 h after the fat meal. PPL in the Mod trial (267 ± 50 mg·dl-1·8 h) was lower compared with that in either Con (439 ± 81 mg·dl-1·8 h) or Low (403 ± 91 mg·dl-1·8 h) trials ( P < 0.05), whereas there was no difference in PPL between Con and Low trials ( P > 0.05). High-density lipoprotein cholesterol (HDL-C) and HDL subtype 2 cholesterol were not different between or within trials ( P > 0.05). Postprandial insulinemia was lower in the Mod trial (20.5 ± 5.7 μIU·ml-1·8 h;...