Quality of Life in Renal Transplant Recipient and Donor (original) (raw)

Objectives. Quality of life (QoL) assessment in renal transplant patients has become an important tool in evaluating outcomes. In this work the QoL of the renal transplant donor and recipient are compared to healthy, age-and BMI-matched individuals. Materials and Methods. The donors were all living related. The immunosuppression protocol was prednisolone, cyclosporine/tacrolimus, and mycophenolate mofetil/azathioprine. Renal function was stable. Quality of life was assessed by KDQOL-SF-36. It includes 36 items divided into 8 scales. Results. Comparison among healthy subjects (n ¼ 20), kidney donor (n ¼ 20), vs recipients (n ¼ 40) for age was 35 AE 8, 40 AE 11, vs 37 AE 10 years (P ¼ NS), and BMI was 23 AE 5, 21 AE 4, vs 21 AE 4 kg/m 2 (P ¼ NS). The mean duration of transplantation of donor and recipients was 22 AE 11 vs 28 AE 25 months (P ¼ NS). Items in SF-36 among 3 groups, respectively, showed general health scores of 48 AE 23, 60 AE 20, vs 59 AE 20; physical functioning 61 AE 28, 84 AE 23, vs 76 AE 265; role physical 31 AE 38, 70 AE 44, vs 636 AE 53; pain 79 AE 36, 73 AE 23, vs 69 AE 25; emotional wellbeing 63 AE 17, 74 AE 14, vs 73 AE 34; social function 83 AE 20, 95 AE 8, vs 91 AE 15, and energy/ fatigue 57 AE 17, 62 AE 16, vs 58 AE 15; (P ¼ NS) was similar in all groups. Correlation studies showed strong positive association of all the items with each other.