Low Birth Weight and First Week Neonatal Mortality in a Tertiary Level Hospital in Bangladesh (original) (raw)

Neonatal Mortality in Association with Low Birthweight

2020

Aim: 730 low birth weight (LBW) neonates and 1460 controls were selected from 13,123 neonates born from Mayo Hospital Lahore from June 2019 to May 2020, and were compared for mortality in the first seven and up to 28 days of life (early neonatal period). Methods: In this study all low birth weight newborns are divided according to four subgroups of birth weight, and the mortality within the first seven (early neonatal mortality) and up to twenty-eight days of life (neonatal mortality) is examined in both groups. Results: Part of the results are as follows: I-low infants comprise 5.6% of total newborns, 2-14.3% of LBW neonates die within the first seven days of life, 3-75% of very LBW neonates (less than 1500 g) die within the first seven days of life, 4-low birth weight neonates have a mortality rate twenty four times that of normal birth weight infants in the first and fourth weeks of life, 5-neonatal mortality rate in this study was 18 per thousand. Conclusion: In conclusion, our recommendation is for provision of the first line of approach i.e. special intensive care is of primary importance for helping the survival of premature infants.

Mortality and morbidity of very low birth weight and extremely low birth weight babies in neonatal period

International Journal of Contemporary Pediatrics, 2019

Background: Preterm birth is one of the major clinical problems in neonatology as it is commonly associated with perinatal mortality, serious neonatal morbidity and in some cases, it leads to childhood disability. The objective of this study was to find out the outcomes of VLBW and ELBW babies in the form of mortality and morbidity in neonatal period.Methods: A cross sectional study was conducted in SNCU, MKCG Medical College, Berhampur, Odisha between 2011 to 2013. All babies with birth weight less than 1500gm, admitted between days 1 to day 7 of life were enrolled in the study. Babies were broadly divided in to two groups i.e.VLBW group (weight 1000-1499gm) and ELBW group (weight<1000gm). Details of antenatal history, sociodemographic profile and birth history including significant events were noted. Outcome measures included were death, cured and with sequelae.Results: Total number of babies enrolled in this study were two hundred twelve (n=212) and following observations were...

A Study on Very Low Birth Weight Babies Admitted in Nicu

GLOBAL JOURNAL FOR RESEARCH ANALYSIS, 2020

Background: Very low birth weight (VLBW) neonates are at high risk for morbidity and mortality. Preterm birth is one of the major clinical problems in Obstetrics and Neonatology. Aim & Objective: To study morbidity and mortality pattern of VLBW neonates admitted to NICU at Department of Pediatrics, Civil hospital, Ahmedabad. Methodology: This cross-sectional prospective observational study was performed on all hospitalized VLBW neonates. Their course during hospitalization and relevant was documented in pre designed performa. Results: In the present study, out of 1748 neonates, 374 (21.39%) were VLBW with 69% males. Mean gestational age was 31.3±1.8 weeks; mean birth weight 1279±193 grams. Common morbidities in VLBW neonates are Neonatal jaundice, Probable sepsis, Apnea of prematurity and RDS. Mortality rate is improved with increasing gestational age and weight. Conclusion: Birth weight and mechanical ventilation are the 2 major factors responsible for mortality. A decline in the m...

Study of variables affecting mortality among extramural very low birth weight neonates in tertiary care centre: a prospective observational study

International Journal of Contemporary Pediatrics

Background: Over the past few decades, the burden of extramural very low birth weight (VLBW) neonates is increasing due to advances in obstetrics services. Objective of present study was to know variables affecting mortality in these neonates. Methods: A prospective observational study was conducted at department of paediatrics, government medical college and hospital, Nagpur, India over a period of 2 years. Out-born neonates admitted in this tertiary care centre with birth weight between 1000-1499 gm were included in the study. Proper antenatal, natal history were taken and data was collected using data collection sheet. All subjects were followed up till discharge or death whichever was earlier. Results: Significant demographic factors associated with neonatal mortality were found out to be place of birth, birth attendant, distance travelled and transport time. Neonatal factors which significantly associated with mortality were found out to be hypothermia and SpO2 less than 90%....

Clinical Study of Morbidity and Mortality Pattern of Preterm Very Low Birth Weight Babies in Neonatal Period

Scholars Journal of Applied Medical Sciences, 2022

Background: There are multiple factors responsible for preterm delivery. It is difficult to completely separate factors associated with prematurity from those are associated with 'IUGR [4]. Objective: To determine morbidity and mortality pattern of preterm very low birth weight babies in neonatal period. Methods: A total number of 200 preterm very low birth weight babies consecutively admitted in this hospital were enrolled into this study. The information about the babies gathered from the history and physical examination and recorded within 24 hours of admission. Each infant was reassessed daily to record the progress and to document any new complication. In his study 50% was male and 50% was female babies. Among them 8.5% was extremely Low birth weight, 1.5% was incredibly low birth weight babies. About 64.5% of preterm VLBW babies were associated with multiple pregnancy- among them 57.1% twin pregnancy and 7.5% triplet pregnancy. Each baby had one or more problems -infection...

Retrospective Evaluation of Frequency, Morbidities and Mortality of Low Birth Weight Infants

Southern Clinics of Istanbul Eurasia, 2019

The aim of this study was to determine the frequency, morbidity, and mortality of low birth weight (LBW) infants born in a single hospital and to compare this group with infants of normal birth weight. Methods: Infants born in our hospital between January 1, 2013 and December 31, 2017 with a birth weight <2500 g were included in the study group. Babies with a birth weight >2500 g were randomly selected as a control group. The demographic and clinical characteristics, neonatal intensive care unit (NICU) hospitalization, etiology, morbidity, presence of asphyxia, and mortality were recorded and statistically analyzed. Results: In a 5-year period, the frequency of LBW infants (<2500 g) was 8.72% (n=2120). Among LBW infants, there were more females than males (p<0.001). The median first and fifth minute Apgar score in the study group was 7 and 8, while it was 8 and 9 in the control group, which yielded a statistically significant difference between the groups (p<0.001). Mothers younger than 20 years and over the age of 35 years were found to have a statistically significantly greater number of babies with LBW (p=0.041 and p=0.028). The mortality rate in LBW infants was determined to be 20 in 1000 live births. The rate of asphyxia observed among LBW infants and newborns with normal birth weight was found to be 0.6% and 0.28%, respectively. It was observed that 66% of newborns with LBW required hospitalization in the NICU, compared with 16% of those with a normal birth weight. The leading etiologies for NICU admission among LBW infants were sepsis (n=738, 34.81%), respiratory distress syndrome (RDS) (n=634, 29.9%), and transient tachypnea of the newborn (TTN) (n=489, 23.99%). When compared with the control group, RDS, TTN, congenital pneumonia, sepsis, hyperbilirubinemia, hypoglycemia, polycythemia, and feeding intolerance were more frequent among the LBW group (p<0.005). The leading morbidities among LBW infants were retinopathy of prematurity (n=177, 8.35%), anemia (n=111, 5.24%), bronchopulmonary dysplasia (n=49, 2.38%), intraventricular hemorrhage (n=32, 1.51%), and necrotizing enterocolitis (n=16, 0.75%). Conclusion: The frequency of low birth weight has varied over time but continues to be a concern. Since Apgar scores were lower and the rates of asphyxia, hospitalization, morbidity and mortality were all increased among LBW infants, antenatal follow-up of these high risk neonates is essential. Optimum resuscitation and medical care by an experienced NICU team after birth is invaluable.

A study of survival of very low birth weight neonates in a tertiary care hospital

International Journal of Contemporary Pediatrics, 2019

Background: Preterm birth is one of the major clinical problems in Obstetrics and Neonatology as it is associated with perinatal mortality, serious neonatal morbidity and in some cases childhood disability. Very low birth weight (VLBW) neonates comprise between 4-8% of live-births but about one-third of deaths during the neonatal period occur in this group of newborns. Data on the probability of survival of infant in high risk pregnancies can be of great value in guiding management. The objective is to study the survival at discharge of VLBW neonates admitted in a tertiary care hospital.Methods: Retrospective observational study of all VLBW infants admitted in Aditya Hospital NICU over 3 years between 1-7-2011 to 30-6-2014. Descriptive and inferential statistical analysis has been carried out in the present study.Results: In the present study maternal PROM was seen in 32.9% of cases, Preeclampsia in 31.7% of cases which constituted the most important antenatal risk factor for VLBW f...

Predictors of mortality in very low birth weight neonates

Journal of Medical Science And clinical Research, 2019

The objective of the study is to identify the predictors of mortality in very low birth weight neonates. It is a nested case control study in a prospectively assembled cohort. Total 260 inborn VLBW newborn admitted to NICU were enrolled. Mean gestational age was 33.58 ± 4.8 week and mean birth weight was 1256.56 ± 182.8 g. Overall case fatality rate was 50.38%. Preterm delivery, low birth weight, APGAR score at 1 and 5 minute were found to be significant predictors of mortality. VLBW who are critically ill due to disturbance in pulmonary and circulatory physiology have a very high risk of mortality.

The Effect of Low Birth Weight (LBW) on Neonatal Death in Gorontalo City

International Journal of Health Science & Medical Research, 2023

Indonesia is a developing country with high maternal and infant mortality rates. One of the causes of infant mortality in Indonesia is the incidence of Low Birth Weight (LBW) of 38.85%. The number of neonatal deaths in Gorontalo City between 2018-2021 is 83 cases. The novelty of this research is the effect of LBW on neonatal death. This study aims to see the impact of LBW on neonatal mortality in Gorontalo City after controlling for maternal risk factors in the form of a history of complications and the frequency of ANC. The research design used was analytic with a case-control approach. The sample in this study consisted of 30 cases and 60 controls. The results of the survey show that from the effects of bivariate analysis, the history of complications variable has an Odds Ratio Crude value of 55 and an Odds Ratio Adjusted of 13 and the Mantel-Haenszel test value: p-value <α (0.000 <0.05). In contrast, Antenatal Care has an Odds Ratio Crude value of 28 and Odds Ratio Adjusted by 17 and the value of the Mantel-Haenszel test: p-value <α (0.000 <0.05). The Odds Ratio value for LBW is 20 with a p-value <α (0.000 <0.05). This study concludes that LBW has a 20 times risk of neonatal death (95% CI = 6.506-61.485).

Maternal antenatal profile and immediate neonatal outcome in very low birth weight babies

IP Innovative Publication Pvt.Ltd, 2017

Objective: To find out maternal risk factors associated with VLBW babies and study maternal risk factors associated with morbidity and mortality of VLBW babies. Materials and Method: The study was a prospective cohort analysis of case records of 110 inborn VLBW babies admitted in Neonatal intensive care unit, of a Teaching hospital during the period of 1 year. Pregnant mother after 24 weeks of gestation were followed up till delivery to report outcome and impact of maternal antenatal profile on VLBW. For calculation of neonatal mortality or morbidity, delivered babies were to be followed up to discharge or death. Morbidity and mortality were compared according to birth weight and gestational age of baby. Only those causes of morbidity where statistical significance with relation to such maternal antenatal factors could be drawn, were studied by using Chi-square test. Results: Majority (81.82%) mothers of VLBW babies had adverse risk factors. Anemia, PROM >=12 hours and PIH were the commonest adverse maternal factors associated with very low birth weight babies. Majority (75.45%) VLBW babies developed one or other kinds of morbidity. The commoner morbidity in VLBW were neonatal sepsis (30%), RDS (19.09%) and NNH (18.18%). The mortality in VLBW babies was only 21.81%. RDS (50%) was the commonest cause of death in VLBW, followed by sepsis (16.6%).The mortality was highest in babies weighing less than 750 gram and less than 28 weeks of gestation. Both morbidity and mortality decreased significantly in babies with higher birth weight. APH, multiple pregnancy and LSCS had statistically significant association (p<0.001) with RDS in VLBW babies. Presence of PROM >=12 hours and maternal fever increased the risk of neonatal sepsis. Presence of PIH, abnormal presentation, multiple pregnancies and meconium staining of liquor were significantly associated with asphyxia. Conclusion: In our study, various adverse maternal factors were associated with very low birth weight and their morbidities. The identification of adverse maternal factors and its appropriate management can lead to better outcome of the baby. Introduction The birth weight is an indicator which gives us an idea about the quality of life, the socioeconomic status, health awareness and nutritional status of the community. The birth weight in all population groups is the single most determinant of the chances of the newborn to survive and experience normal growth and development. (1) Very low birth weight has been defined as birth weightless than 1.5kg, birth weight being taken preferably within first hour of life before significant weight loss occurs. In India around 3% babies are VLBW babies. (2) VLBW can be caused by either a short gestational period or retarded intrauterine growth or a combination of both. Prematurity is usually defined as gestational age less than 37 weeks and small for gestational age (SGA) or small for date (SFD) babies are those with birth weight less than 10 th percentile for their gestational age. (2) As babies weighing less than 2kg are more vulnerable to increased morbidity and mortality, they deserve priority in admission to special care nurseries and by this criterion alone, 10% of newborn babies in India qualify for admission to special care nurseries. (3) The common causes of morbidity and mortality in VLBW babies include birth asphyxia, respiratory