Disease-specific quality of life is associated with anxiety and depression in patients with acne (original) (raw)

Evaluation of anxiety, depression, and quality of life in patients with acne vulgaris, and quality of life in their families

Dermatologica Sinica, 2016

Background/Objectives: Dermatological diseases not only affect patients' lives but also the lives of their family members. Our aim was to evaluate anxiety and depression risk in patients with acne vulgaris and the effect of acne vulgaris on quality of life of the patients and their families. Methods: A total of 125 patients with acne vulgaris, 110 of their family members, and 100 healthy volunteers were included in the study. Patients with acne vulgaris were requested to complete the Acne Quality of Life Scale (AQOL) and Hospital Anxiety and Depression Scale (HAD) at the time of the first admission and 2 months later. The healthy volunteers were only asked to complete the HAD, and the family members filled out the Family Dermatology Life Quality Index (FDLQI) at the time of the first admission and 2 months later. Results: The acne and control groups showed no significant differences between the HAD anxiety subscale (HAD-A) and HAD depression subscale (HAD-D) scores. The mean AQOL score of the patients was 6.8 ± 5.3. AQOL scores were positively correlated with HAD-A, HAD-D and FDLQI scores. The mean score of the FDLQI was 7.6 ± 5.3. FDLQI scores showed a statistically significant change after 2 months (p ¼ 0.001). Conclusion: Acne vulgaris does not have an effect on quality of life and the risk of anxiety or depression. In the cases of acne, when the quality of life decreases, the risk of depression as well as anxiety increases and the quality of life of the family members is negatively affected. Acne vulgaris negatively affects the quality of life of the family members of the patients.

The Psychological Impacts of Acne

Pakistan Journal of Medical and Health Sciences

Objective: To determine the frequency of different category of Dermatology Life Quality Index (DLQI) in patients with Acne Vulgaris visiting to tertiary care hospital. Study Design: Descriptive Cross-Sectional Study. Place and Duration: This study was conducted at the Department of Dermatology, Shaheed Mohtarma Benazir Bhutto Medical University, Larkana, Pakistan during the period from August 23, 2019 to February 22, 2020. Materials and Methods: All patients who fulfilled the inclusion criteria and visited to SMBBMU, Larkana were included in the study. Informed consent was taken after explaining the procedure, risks and benefits of the study. In our study, patients with acne vulgaris were diagnosed on the basis of relevant clinical history and examination. Patients were asked to fill the DLQI questionnaire themselves to assess the DLQI. All the collected data were entered into the proforma attached at the end and used electronically for research purpose. Results: Mean ± SD of age wa...

An evaluation of the quality of life in acne -A prospective study at a tertiary care hospital

IP Innovative Publication Pvt. Ltd, 2017

Acne is a disorder of the pilosebaceous unit that causes considerable cosmetic effect. An individual affected by acne is adversely affected psychologically. Several studies in the past have shown that acne is associated with decrease in health-related quality of life. These individuals suffer from frustration, embarrassment and lack of self-confidence. (1) This prospective study was undertaken to determine the impact of acne vulgaris on quality of life among patients of different grades of acne patients in various age groups using a questionnaire Cardiff acne disability index (CADI). (2) In our study the females were more affected than male. The most common age group involved as 21-25 years. In our study we found that the males were more concerned about the acne and the incidence of depressive symptoms was more in them as compared to females.

Quality of life in acne patients: A clinical and Dermatology Life Quality Index (DLQI) based cross-sectional study

Journal of Pakistan Association of Dermatology, 2019

Objective To detect the impact of acne vulgaris on quality of life and assess correlation between disease severity, complications and decreased life quality. Methods This cross-sectional study of one-year duration involving acne patients of 18-30 years was carried out after institutional Ethics Committee clearance. After written informed consent, patients filled a proforma including demographic data, treatment and previous psychiatric history. Clinical grade of acne and severity of pigmentation and scarring were noted. Acne severity was classified as mild, moderate or severe and DLQI was noted. Statistical analysis was performed with the Statistical Package for the Social Sciences (SPSS version 15.0), Chi-square test and Pearson’s correlation coefficient. Results Overall mean DLQI was 7.84 (females 8.02, males 7.82) showing no significant difference between the genders. There was no association seen between DLQI scores severity and complications like pigmentation ( p =0.198) and sca...

Quality Of Life And Depression Among Young Patients Suffering From Acne

Journal of Ayub Medical College, Abbottabad : JAMC, 2019

BACKGROUND In addition to depression, acne has considerable negative effects on the quality of life (QOL) which is estimated to be equal to that reported by patients with other chronic diseases. The immense suffering of ace patients both terms of depression and deterioration in quality of life and subsequent compromised social, vocational and academic performance makes them seek professional help more often for non-cutaneous manifestations e.g., poor body image, anxiety, depression etc. This study was conducted to determine the prevalence of depression and status of quality of life in acne patients visiting outpatient dermatology. METHODS This was a cross-sectional study conducted in the outpatient dermatology department of Ayub Teaching Hospital, Abbottabad between January and August 2018. The 74 consecutive acne cases visiting the dermatology OPD during the study period between the ages of 13 and 30 years were assessed for depression and QOL. Data was collected by Dermatology life...

Comparison of depression, anxiety and life quality in acne vulgaris patients who were treated with either isotretinoin or topical agents

International Journal of Dermatology, 2009

Background Since the introduction of isotretinoin to the market, many adverse psychiatric effects, including depression, anxiety and suicide attempts were reported. The aim of this study was to determine whether patients with acne who were treated with isotretinoin experienced significant increases in psychiatric symptoms over a 4-month period compared with patients who received topical acne therapy.Methods Seventy-eight acne patients were allocated either to isotretinoin treatment (study group) (n = 37) or to topical treatment (control group) (n = 41). Their psychological status was evaluated at the baseline, second and fourth months of the treatment. All patients were required to complete the dermatology life quality index (DLQI), the Hospital anxiety and depression (HAD) scale, and the beck depression inventory (BDI).Results The two groups were not different from each other in terms of DLQI, BDI, HAD-A, HAD-D and total HAD scores at baseline. However, at the end of the second month quality of life was more impaired in the topical treatment group compared to the isotretinoin group (P < 0.05), and there were no difference between two groups in terms of BDI, HAD-A, HAD-D, and total HAD scores (P > 0.05). At the end of fourth month quality of life and all psychological test scores had improved more in the isotretinoin group compared to topical treatment group (P < 0.05).Conclusion Results of the present study indicate that there is no increase in depressive and anxiety symptoms in the isotretinoin treatment group compared to that in the topical group. Instead, successful treatment of acne seems to improve both depressive and anxiety symptoms and improve quality of life.

Psychosocial Aspects of Adult Acne: Data from 13 European Countries

Acta Dermato Venereologica

Acne is one of the commonest dermatological diseases and this is a first large-scale case control study aiming to reveal psychosocial impact. This analysis was based on a multicenter study including 213 acne patients over 18 years and 213 age-sex matched controls. We found that patients with acne are more likely to express anxiety, depression, pain and discomfort, and suicidal thoughts than the general population. Clinicians must be alert to these symptoms and where present consider the possibility of an underlying psychiatric component. This awareness may improve recognition of patient concerns and allow clinicians to optimize treatment. The link between acne and psychiatric morbidities has been demonstrated in many studies; however, large scale studies aiming to reveal the psychosocial impact of acne are rare. The aim of this study was to assess the psychological burden of adult acne patients. This analysis was based on a multicenter study including 213 acne patients and 213 controls from 13 European countries. The Hospital Anxiety and Depression Scale (HADS), Dermatology Life Quality Index, and EuroQol 5 dimensions 3 levels scores of the patients with acne were analyzed. Patients with acne (n = 213) had higher HADS scores for anxiety (mean ± standard deviation 6.70 ± 3.84) and depression (3.91 ± 3.43) than the controls (p < 0.001 for both). For patients with acne, 40.6% reported that they were very concerned about their skin disease, 12.3% had suicidal ideation, and, among those, 10 (4%) patients implied that acne was the cause of their suicidal thoughts. After adjusting for other variables, patients who had suicidal ideation (p = 0.007, and adjusted odds ratio 3.32 [95% confidence interval (CI): 1.39-7.93]) and stressful life events (p < 0.001, and adjusted OR 5.85 [95% CI: 2.65-12.86]) had a greater chance of fulfilling the HADS criteria for anxiety. This study highlights the need for a psychotherapeutic approach in order to recognize the concerns of acne patients and optimize their treatment.

Impact of Acne Vulgaris on Patients' Quality of Life

The Medical Journal of Cairo University, 2019

Background: Acne is a common inflammatory skin disorder manifested by comedones, papules and pustules mainly at face. Acne may be complicated by nodules, cysts and residual scarring that affect life quality. Aim of Study: Was to determine the impact of acne on health related quality of life comparing with normal healthy control. Patients and Methods: The current study included 400 subjects aged from 13 to 18 years old. They were divided into patients' group and control group, each included 200 subjects with age and sex matched. The patients group with mean age of (15.6 ± 1.54); the female patients constituted 113 (56.5%). According to acne severity, the patient group included moderate acne (117) patients and severe acne in 83 patients. The control group included 114 (57%) females. Full history taking, general examination including measuring of BMI, dermatologic examination to determine site, extent and grading. Results: Acne negatively affects self-perception in comparison with control while no difference in social role between cases and control. There is a positive correlation between self-perception and the other domains, while there is a negative correlation between acne symptoms and other domains of quality of life. Conclusions: Acne can affects social and psychologic impact on life quality. Recommendations: Assessment of life quality in acne patients is a must and should be taken into consideration before deciding line of treatment.

A cross-sectional study on quality of life among acne vulgaris patients

International Journal of Research in Medical Sciences, 2016

Background: In India, prevalence data from dermatology clinic in a teaching hospital in Varanasi reported acne in 50.6% of boys and 38.13% of girls in the age group 12-17 years. Though it is considered to be merely a cosmetic problem, it is associated with considerable psychological impairment which is comparable with certain chronic diseases. Acne patients are prone to low self-esteem, low self-confidence and social dysfunction which may lead to anxiety, depression, obsessive compulsiveness and sometimes suicidal ideation. Acne affects the functional abilities of individuals and patients have higher rate of unemployment when compared to those without acne. Acne also may have negative impact on personal relationships, sports activities and employment opportunities in teens and young adults. The management of acne must take into account the impact of acne on the patient's quality of life. So the present study was carried out to determine the impact of acne and its clinical severity on quality of life among patients of different grades of acne patients in various age groups. Methods: The current cross sectional study was conducted in Patients diagnosed as acne vulgaris attending OPD of PCMS and RC Bhopal (India) in department of dermatology for a period of 2 year. (November 2012-October 2014). 300 patients attending the Dermatology OPD with diagnosis of acne vulgaris were taken for the study. Patients aged 16-35 years were included in our study. A detailed history was taken after obtaining consent from all the participants of study. Cardiff Acne disability index (CADI) and Dermatology life quality index (DLQI) were administered on patients to determine the impact of acne vulgaris on quality of life (QOL). Data was analyzed to compare the quality of life indices (CADI and DLQI) for duration and severity of acne. Results: Mean age of study population was 20.69 years. There was a male preponderance with ratio of 1.04:1 (M:F). According to this study 49% of patients had acne vulgaris for less than 1year. In present study maximum number 63.7% of patients presented with lesions over face followed by 14.7% of patients having lesions over face and back. According to DLQI scores of acne showed no effect in 4.3% of the patients, small effect in 26.3% of the patients, moderate effect in 38.7% of patients, very large effect in 29% of patients and extremely large effects on 1.7% of patients. According to CADI scores of acne showed low effect in 31.3% of the patients, majority had medium effect in 56.7% of patients and high effect was seen on 12 % of patients. Conclusions: Overall our study showed that quality of life is significantly impaired in patients of severe acne vulgaris. Use of these simple QOL measures as a part of integral clinical strategy will improve the outcome.

Cardiff Acne Disability Index Based Quality Of Life In Acne Patients, Risk Factors And Associations

Journal of Liaquat University of Medical & Health Sciences, 2018

BACKGROUND: Acne Vulgaris is a frequently seen dermatological condition having physical and psychosocial implications. Current study aims to assess Quality of life (QoL) in acne patients and study the associated risk factors. METHODOLOGY: This descriptive cross sectional study was conducted in 6 months duration at Dept. of Dermatology, Rawal Institute of Health Sciences Islamabad after ethical approval. Total 205 cases of acne (age>12 years) were included. Patients with severe systemic illness and endocrine disease were excluded. Global Acne Grading Scale (GAGS) was used to grade acne as mild, moderate or severe. Quality of life assessed by Cardiff Acne disability index (CADI) with outcome as no impairment, mild impairment, moderate impairment or severe impairment. Data analyzed via SPSS version 17 with Chi-square test applied for significance. The p-value <0.05 considered to be statistically significant. RESULTS: Among 205 acne cases (24% males and 76% females), mean age was 25+5.7 (14-36) years. As per GAGS score; mild acne was present in 45.4%, moderate acne(44%), severe acne (8.35%) and very severe acne (2.4%). As per CADI score, there was no impairment in 7.3%, mild impairment (19.5%), moderate impairment (61%) and severe impairment in (12%). The impaired QoL was found to be associated with gender, socioeconomic class, education, acne grade, obesity and use of alternative medicine (p<0.05). CONCLUSION: Acne vulgaris significantly impairs QoL in adolescents to varying degrees. Higher grade of acne, female gender, obesity, illiteracy and poverty are the proposed risk factors for impaired QoL in acne cases. Early identification of acne cases at risk of impaired Qol may be helpful to take QoL measures like counseling and psychological intervention in parallel with medical management. This may improve the social and psychological wellbeing of acne cases.