Internalized antibodies to the Aβ domain of APP reduce neuronal Aβ and protect against synaptic alterations (original) (raw)

Internalized Antibodies to the Abeta Domain of APP Reduce Neuronal Abeta and Protect against Synaptic Alterations

Journal of Biological Chemistry, 2007

Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and reduce pathology in a mouse model of Alzheimer disease

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Immunotherapy for Alzheimer's disease: attacking amyloid-â from the inside

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Epitope and isotype specificities of antibodies to β-amyloid peptide for protection against Alzheimer's disease-like neuropathology

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Peripheral anti-Aβ antibody alters CNS and plasma Aβ clearance and decreases brain Aβ burden in a mouse model of Alzheimer's disease

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Intracranial administration of deglycosylated C-terminal-specific anti-Abeta antibody efficiently clears amyloid plaques without activating microglia in amyloid-depositing transgenic mice

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Endogenous murine Aβ increases amyloid deposition in APP23 but not in APPPS1 transgenic mice

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Intraneuronal Aβ immunoreactivity is not a predictor of brain amyloidosis-β or neurofibrillary degeneration

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Peripherally administered antibodies against amyloid β-peptide enter the central nervous system and …

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Immunocytochemical Characterization of Alzheimer Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-í µí»½ Vaccine

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Internalized antibodies to the Aβ domain of APP reduce neuronal Aβ and protect against synaptic alterations (original) (raw)

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