Transcriptional landscape of psoriasis identifies the involvement of IL36 and IL36RN (original) (raw)
Increased IL17A, IFNG, and FOXP3 Transcripts in Moderate-Severe Psoriasis: A Major Influence Exerted by IL17A in Disease Severity
Mariana Lima
Mediators of inflammation, 2016
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Assessment of the Psoriatic Transcriptome in a Large Sample: Additional Regulated Genes and Comparisons with In Vitro Models
Andrew Johnston
Journal of Investigative Dermatology, 2010
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Dissecting the psoriasis transcriptome: inflammatory-and cytokine-driven gene expression in lesions from 163 patients
William R Swindell
BMC Genomics, 2013
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Integrative Responses to IL17 and TNF-α in Human Keratinocytes Account for Key Inflammatory Pathogenic Circuits in Psoriasis
Mayte Suarez-Farinas
2011
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Comparisons of gene expression in normal, lesional, and non-lesional psoriatic skin using DNA microarray techniques
Parimala Anthony
International Journal of Dermatology, 2014
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Cross-Disease Transcriptomics: Unique IL-17A Signaling in Psoriasis Lesions and an Autoimmune PBMC Signature
William R Swindell
J Invest Dermatol, 2016
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The spectrum of mild-to-severe psoriasis vulgaris is defined by a common activation of IL-17 pathway genes, but with key differences in immune regulatory genes
Mayte Suarez-Farinas
The Journal of investigative dermatology, 2016
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Molecular Phenotyping Small (Asian) versus Large (Western) Plaque Psoriasis Shows Common Activation of IL-17 Pathway Genes, but Different Regulatory Gene Sets
Mayte Suarez-Farinas
The Journal of investigative dermatology, 2015
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IL-17 Induces an Expanded Range of Downstream Genes in Reconstituted Human Epidermis Model
Andrea Chiricozzi
PLoS ONE, 2014
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Gene expression profiling of Japanese psoriatic skin reveals an increased activity in molecular stress and immune response signals
Hidetoshi Inoko
Journal of Molecular Medicine, 2005
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Gene Expression Profiles Normalized in Psoriatic Skin by Treatment with Brodalumab, a Human Anti-IL-17 Receptor Monoclonal Antibody
Chris Russell
The Journal of Immunology, 2014
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Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity
Oliver Fitzgerald
Nature Genetics, 2012
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Decreased expression of IL-17 pathway genes in blood in patients with plaque psoriasis treated with the anti-IL-17A monoclonal antibody, ixekizumab
Wendy Komocsar
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Palmoplantar pustular psoriasis (PPPP) is characterized by activation of the IL-17A pathway
Mayte Suarez-Farinas
Journal of Dermatological Science, 2017
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The psoriatic transcriptome closely resembles that induced by interleukin-1 in cultured keratinocytes: dominance of innate immune responses in psoriasis
Frank Burslem
The American journal of pathology, 2007
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The Psoriatic Transcriptome Closely Resembles That Induced by Interleukin-1 in Cultured Keratinocytes
Frank Burslem
The American Journal of Pathology, 2007
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Characterization of the interleukin-17 isoforms and receptors in lesional psoriatic skin
Lars Iversen
British Journal of Dermatology, 2009
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Cross-Study Homogeneity of Psoriasis Gene Expression in Skin across a Large Expression Range
Chris Russell
PLoS ONE, 2013
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Gene expression profiling of peripheral blood mononuclear leukocytes from psoriasis patients identifies new immune regulatory molecules
Hans-Juergen Thiesen
European journal of dermatology : EJD
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Psoriasis and Systemic Inflammatory Diseases: Potential Mechanistic Links between Skin Disease and Co-Morbid Conditions
James Krueger
Journal of Investigative Dermatology, 2010
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IL-17A is essential for cell activation and inflammatory gene circuits in subjects with psoriasis
James Krueger
Journal of Allergy and Clinical Immunology, 2012
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