Formation of stable adducts and absence of depurinating DNA adducts in cells and DNA treated with the potent carcinogen dibenzo[a,l]pyrene or its diol epoxides (original) (raw)

DNA adduct formation and persistence in rat tissues following exposure to the mammary carcinogen dibenzo[a,l]pyrene

Jamal Arif

Carcinogenesis, 1999

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Identification and Quantitation of Dibenzo[a,l]pyrene-DNA Adducts Formed by Rat Liver Microsomes in Vitro: Preponderance of Depurinating Adducts

Ryszard Jankowiak

Biochemistry, 1995

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Identification and Quantification of the Depurinating DNA Adducts Formed in Mouse Skin Treated with Dibenzo[a,l]pyrene (DB[a,l]P) or Its Metabolites and in Rat Mammary Gland Treated with DB[a,l]P

Eleanor Rogan

Chemical Research in Toxicology, 2005

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Comparison of the morphological transforming activities of dibenzo[a,l]pyrene and benzo[a]pyrene in C3H10T1/2CL8 cells and characterization of the dibenzo[a,l]pyrene-DNA adducts

Dhimant Desai

Carcinogenesis, 1997

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Identification and Quantification of DNA Adducts in the Oral Tissues of Mice Treated with the Environmental Carcinogen Dibenzo[a,l]pyrene by HPLC-MS/MS

Jyh-ming Lin

Chemical Research in Toxicology, 2011

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Comparison of cytochrome P450- and peroxidase-dependent metabolic activation of the potent carcinogen dibenzo[a,l]pyrene in human cell lines: formation of stable DNA adducts and absence of a detectable increase in apurinic sites

Albrecht Seidel

Cancer research, 1999

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Identification and Quantification of Stable DNA Adducts Formed from Dibenzo[ a,l ]pyrene or Its Metabolites in Vitro and in Mouse Skin and Rat Mammary Gland

Ercole Cavalieri

Chemical Research in Toxicology, 2005

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Structure, Conformations, and Repair of DNA Adducts from Dibenzo[ a , l ]pyrene: 32 P-Postlabeling and Fluorescence Studies

Ryszard Jankowiak

Chemical Research in Toxicology, 1998

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Quantification of benzo[a]pyrene diol epoxide DNA-adducts by stable isotope dilution liquid chromatography/tandem mass spectrometry

Trevor Penning, Ian Blair

Rapid Communications in Mass Spectrometry, 2006

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Identification of a Novel, N7-Deoxyguanosine Adduct as the Major DNA Adduct Formed by a Non-Bay-Region Diol Epoxide of Benzo[a]pyrene with Low Mutagenic Potential

Jackson Lay

Biochemistry, 1994

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Microsome-mediated bioactivation of dibenzo[a,l]pyrene and identification of DNA adducts by 32P-postlabeling

Jamal Arif

Carcinogenesis, 1997

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Effect of nuclear environment on the distribution of benzo[ a ]pyrene diol epoxide-induced adducts in the HPRT gene of human fibroblasts

Justin McCormick

Carcinogenesis, 1996

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Sequence dependence of benzo[a]pyrene diol epoxide-DNA adduct conformer distribution: A study by laser-induced fluorescence/polyacrylamide gel electrophoresis

Ryszard Jankowiak

Chemical Research in Toxicology, 1994

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32P-Postlabeling analysis of lipophilic DNA adducts resulting from interaction with (±)-3-hydroxy-trans-7,8-dihydroxy-9,10-epoxy-7,8,9,10-tetrahydro-benzo[a]pyrene

Nancy Shappell

Chemico-Biological Interactions, 1999

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Investigation of the genotoxicity of dibenzo[c,p]chrysene in human carcinoma MCF-7 cells in culture

Tuan Nguyen

Chemico-Biological Interactions, 2006

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Comparison of the genotoxic activities of the K-region dihydrodiol of benzo[ a]pyrene with benzo[ a]pyrene in mammalian cells: morphological cell transformation; DNA damage; and stable covalent DNA adducts

Maria Pimentel

Mutation Research-genetic Toxicology and Environmental Mutagenesis, 2002

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Regulation of Benzo[ a ]pyrene-Mediated DNA- and Glutathione-Adduct Formation by 2,3,7,8-Tetrachlorodibenzo- p -dioxin in Human Lung Cells

Stacy Gelhaus

Chemical Research in Toxicology, 2011

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32P-Postlabelling analysis of dibenz[a,j]acridine-DNA adducts in mice: identification of proximate metabolites

G. Talaska

Chemico-Biological Interactions, 1995

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H2AX phosphorylation in A549 cells induced by the bulky and stable DNA adducts of benzo[a]pyrene and dibenzo[a,l]pyrene diol epoxides

Ian Cotgreave

Chemico-Biological Interactions, 2009

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Dibenzo[a,l]pyrene induced DNA adduct formation in lung tissue in vivo

William Baird

Cancer Letters, 2005

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Stable Expression of Human Cytochrome P450 1B1 in V79 Chinese Hamster Cells and Metabolically Catalyzed DNA Adduct Formation of Dibenzo[ a , l ]pyrene

Volker Soballa, Albrecht Seidel

Chemical Research in Toxicology, 1998

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Patterns of DNA adduct formation in liver and mammary epithelial cells of rats treated with 7,12-dimethylbenz(a)anthracene, and selective effects of chemopreventive agents

Cristina Cartiglia

Cancer research, 1999

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Evidence for the involvement of a diol-epoxide in the binding of 7,12-dimethylbenz(a)anthracene to DNA in cells in culture

J. Nebzydoski

Chemico-Biological Interactions, 1978

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Comparative Tumorigenicity and DNA Damage Induced by Dibenzo[def,p]chrysene and Its Metabolites in the Mouse Ovary

Karam El-Bayoumy

Chemical Research in Toxicology, 2018

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