original ) (raw )Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice
Roberta Bianchi
Carcinogenesis, 2006
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N-methylpurine DNA glycosylase plays a pivotal role in the threshold response of ethyl methanesulfonate-induced chromosome damage
George Johnson , Z. Zaïr , S. Doak
2011
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DNA Damage and Cytotoxicity of 2-Chloroethyl (Methylsulfonyl)methanesulfonate (NSC 338947) Produced in Human Colon Carcinoma Cells with or without Methylating Agent Pretreatment
Neil Gibson
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Overexpression of N-methylpurine-DNA glycosylase in Chinese hamster ovary cells renders them more sensitive to the production of chromosomal aberrations by methylating agents--a case of imbalanced DNA repair
Bernd Kaina
Mutation research, 1995
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The Implications of DNA Methylation for Toxicology: Toward Toxicomethylomics, the Toxicology of DNA Methylation
Moshe Szyf
Toxicological Sciences, 2011
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Roles of DNA repair methyltransferase in mutagenesis and carcinogenesis
Kunihiko Sakumi
Journal of Human Genetics, 1997
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Methyl bromide causes DNA methylation in rats and mice but fails to induce somatic mutations in λlacZ transgenic mice
Vasiliki Pletsa
Cancer Letters, 1998
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Comparison of the biological effects of MMS and Me-lex, a minor groove methylating agent: Clarifying the role of N3-methyladenine
Gilberto Fronza , Barry Gold
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2014
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A Chemical and Genetic Approach Together Define the Biological Consequences of 3-Methyladenine Lesions in the Mammalian Genome
Barry Gold
Journal of Biological Chemistry, 1998
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Physicochemical studies of human O6-methylguanine-DNA methyltransferase
Debasish Bhattacharyya
European Journal of Biochemistry, 1990
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Accumulation of O 6 -Methylguanine in Human DNA after Therapeutic Exposure to Methylating Agents and Its Relationship with Biological Effects
christos valavanis
Environmental Health Perspectives, 1993
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Enhanced survival and reduced mutation and aberration frequencies induced in V79 chinese hamster cells pre-exposed to low levels of methylating agents
Bernd Kaina
Mutation research, 1982
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Substrate binding pocket residues of human alkyladenine-DNA glycosylase critical for methylating agent survival
Leona Samson
DNA Repair, 2008
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Inducibility of the DNA repair gene encoding O6-methylguanine-DNA methyltransferase in mammalian cells by DNA-damaging treatments
Bernd Kaina
Molecular and cellular biology, 1991
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DNA Damage and Cytotoxicity Induced by Minor Groove Binding Methyl Sulfonate Esters †
Gilberto Fronza , Barry Gold
Biochemistry, 2003
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Relationship between DNA Methylation and Mutational Patterns Induced by a Sequence Selective Minor Groove Methylating Agent
Alberto Inga
Journal of Biological Chemistry, 1999
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P XVI B.4 O6-methylguanine is a ubiquitous lesion in human DNA
S. Kaila , Soterios A Kyrtopoulos
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1997
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Changes in de novo DNA (cytosine-5-)-methyltransferase activity in oncogenically susceptible rat target tissues induced by N-methyl-N-nitrosourea
Annie Leszkowicz
Cancer research, 1986
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1,N6-Ethenoadenine Is Preferred over 3-Methyladenine as Substrate by a Cloned Human N-Methylpurine-DNA Glycosylase (3-Methyladenine-DNA Glycosylase)
Sankar Mitra
Biochemistry, 1994
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Mismatch Repair Defects and O6-Methylguanine-DNA Methyltransferase Expression in Acquired Resistance to Methylating Agents in Human Cells
Richard Hampson
Journal of Biological Chemistry, 1997
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The bacterial alkyltransferase-like (eATL) protein protects mammalian cells against methylating agent-induced toxicity
Bernd Kaina
DNA repair, 2015
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Amplification of the DNA Repair Gene O6-Methylguanine-DNA Methyltransferase Associated with Resistance to Alkylating Drugs in a Mammalian Cell Line
Firouz Darroudi
Journal of Biological Chemistry, 1997
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Changes in DNA methyltransferase induced by treatment with N-2-acetylaminofluorene
Carlos Salas
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 1989
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Uracil-DNA glycosylase activity affects the mutagenicity of ethyl methanesulfonate: Evidence for an alternative pathway of alkylation mutagenesis
Barry Glickman
Mutation Research Letters, 1990
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Methylation versus ethylation of DNA in target and nontarget tissues of Fischer 344 rats treated with N-nitrosomethylethylamine
Eric von Hofe
Cancer Research
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Relative efficiencies of the bacterial, yeast, and human DNA methyltransferases for the repair of O6-methylguanine and O4-methylthymine. Suggestive evidence for O4-methylthymine repair by eukaryotic methyltransferases
Leona Samson
The Journal of biological chemistry, 1991
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Mutations associated with base excision repair deficiency and methylation-induced genotoxic stress
Julie Horton
Proceedings of the National Academy of Sciences, 2002
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Mutagenicity of N3-methyladenine: A multi-translesion polymerase affair
Debora Russo , Gilberto Fronza , Barry Gold
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, 2010
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