Neuronal gelsolin prevents apoptosis by enhancing actin depolymerization (original) (raw)

Neuroprotective effects of gelsolin during murine stroke

James Geddes

Journal of Clinical Investigation, 1999

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Inhibition of apoptosis by the actin-regulatory protein gelsolin

Makoto Otsu

The EMBO Journal, 1997

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Caspase-3-Generated Fragment of Gelsolin: Effector of Morphological Change in Apoptosis

Seenu Kothakota

Science, 1997

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Apoptosis in caspase-inhibited neurons

Christiane Volbracht

Molecular medicine (Cambridge, Mass.), 2001

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Structure of the N-terminal half of gelsolin bound to actin: roles in severing, apoptosis and FAF

Leslie Burtnick

The EMBO Journal, 2004

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Evaluation of the neuronal apoptotic pathways involved in cytoskeletal disruption-induced apoptosis

Clemens Allgaier

Biochemical Pharmacology, 2005

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Calpain inhibitors, but not caspase inhibitors, prevent actin proteolysis and DNA fragmentation during apoptosis

Pascal Villa

Journal of Cell Science, 1998

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The Cell Death Pathway Regulates Synapse Elimination through Cleavage of Gelsolin in Caenorhabditis elegans Neurons

Dong Yan, Yishi Jin

Cell Reports, 2015

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Yang, F. et al. Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease. Am. J. Pathol. 152, 379-389

Bruce Teter

American Journal Of Pathology

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Actin is cleaved during constitutive apoptosis

Simon Brown

Biochemical Journal, 1997

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Neuronal caspase-3 signaling: not only cell death

Virve Cavallucci

Cell Death & Differentiation, 2009

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Mechanisms of neural cell death: Implications for development of neuroprotective treatment strategies

Alexander Yakovlev

Neurorx, 2004

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Gelsolin and Related Proteins in Vertebrate Model Organisms

Joanna Niedbalska-Tarnowska

Folia Biologica-krakow, 2019

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Targeting post-mitochondrial effectors of apoptosis for neuroprotection

Oliver Kepp

Biochimica et Biophysica Acta (BBA) - Bioenergetics, 2009

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The actin cytoskeleton as a sensor and mediator of apoptosis

Melissa Desouza

BioArchitecture, 2012

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Inhibition of excitatory neuronal cell death by cell-permeable calcineurin autoinhibitory peptide

Sheng-tian Li, Kazuhito Tomizawa

Journal of Neurochemistry, 2003

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Wang, H. et al. Apoptosis-inducing factor substitutes for caspase executioners in NMDA-triggered excitotoxic neuronal death. J. Neurosci. 24, 10963-10973

Jasmine Lew

The Journal of Neuroscience : The Official Journal of the Society for Neuroscience

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Antibody to caspase-cleaved actin detects apoptosis in differentiated neuroblastoma and plaque-associated neurons and microglia in Alzheimer's disease

Bruce Teter

The American journal of pathology, 1998

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Maier, J. K. et al. The neuronal apoptosis inhibitory protein is a direct inhibitor of caspases 3 and 7. J. Neurosci. 22, 2035-2043

Raouf Fetni

The Journal of Neuroscience : The Official Journal of the Society for Neuroscience

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Caspase-mediated cleavage of actin and tubulin is a common feature and sensitive marker of axonal degeneration in neural development and injury

James Mandell

Acta neuropathologica communications, 2014

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Caspase Activation Is Downstream of Commitment to Apoptosis of Ntera-2 Neuronal Cells

Rosemary Gibson

Experimental Cell Research, 1999

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GABAergic striatal neurons exhibit caspase-independent, mitochondrially mediated programmed cell death

Maria Hughes

Journal of Neurochemistry, 2009

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Upstream control of apoptosis by caspase-2 in serum-deprived primary neurons

Etienne Jacotot

Apoptosis, 2005

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Mitochondria in neurodegenerative apoptosis: An opportunity for therapy?

Ruth Redman

Annals of Neurology, 1998

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Semaphorins as Mediators of Neuronal Apoptosis

I. Ziv, Ronit Shina

Journal of Neurochemistry, 2001

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A potential role for calcium / calmodulin-dependent protein kinase-related peptide in neuronal apoptosis: in vivo and in vitro evidence

Bart Engels

European Journal of Neuroscience, 2007

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Oxidative stress, mitochondrial permeability transition and activation of caspases in calcium ionophore A23187-induced death of cultured striatal neurons

Patrik Brundin

Brain Research, 2000

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Apoptosis: A Key in Neurodegenerative Disorders

Oleksandr Ekshyyan

Current Neurovascular Research, 2004

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Neuronal Apoptosis in Neurodegeneration

Tak Yee Aw

Antioxidants & Redox Signaling, 2007

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Neuroglobin protects nerve cells from apoptosis by inhibiting the intrinsic pathway of cell death

Nigel Birch

Apoptosis, 2010

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Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death

Jasmine Lew

The Journal of Neuroscience, 2004

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Role of caspase-3 in neuronal cell death

Sandra Ceccatelli

Pathophysiology, 1998

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Inhibitory Effect of PACAP on Caspase Activity in Neuronal Apoptosis: A Better Understanding Towards Therapeutic Applications in Neurodegenerative Diseases

Agnieszka Dejda, Hubert Vaudry

Journal of Molecular Neuroscience, 2008

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Multifaceted deaths orchestrated by mitochondria in neurones

Phillip Nagley

Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease, 2010

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