Brain-derived neurotrophic factor Val66Met polymorphism and dexamethasone/CRH test results in depressed patients (original) (raw)

Psychoneuroendocrinology, 2006

Thomas Baghai

Rainer Rupprecht

Daniela Eser

Brigitta Bondy

Cornelius Schüle

P. Zwanzger

P. Zill

Abstract

... In contrast, up-regulation of BDNF has been suggested to mediate the action of antidepressant treatment (Saarelainen et al., 2003). ... Depressive disorder has been demonstrated to be associated with hippocampal atrophy (Sheline et al., 1996; Sapolsky, 2000). ...

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