Enzymatic resolution of 5-hydroxy- and 8-hydroxy-2-tetralols using immobilized lipases (original) (raw)
Enzymatic resolution of 5-hydroxy- and 8-hydroxy-2-tetralols using immobilized lipases
Tetrahedron: Asymmetry, 2009
Abstract
... Recently, we found that the hydrolysis of racemic 2-tetralyl butyrate rac-1a catalyzed by Rhizomucor miehei lipase (RML) immobilized on octyl agarose affords (R)-alcohol (R)-2a with high enantiomeric excess as determined by MTPA ester method. 22. ...
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