Dosimetric variations due to interfraction organ deformation in cervical cancer brachytherapy (original) (raw)

Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology, 2015

Abstract

We quantitatively estimated dosimetric variations due to interfraction organ deformation in multi-fractionated high-dose-rate brachytherapy (HDRBT) for cervical cancer using a novel surface-based non-rigid deformable registration. As the number of consecutive HDRBT fractions increased, simple addition of dose-volume histogram parameters significantly overestimated the dose, compared with distribution-based dose addition.

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