Descemet's Stripping Endothelial Keratoplasty: Safety and Outcomes (original) (raw)

Abstract

To review the published literature on safety and outcomes of Descemet's stripping endothelial keratoplasty (DSEK) for the surgical treatment of endothelial diseases of the cornea.

Loading...

Loading Preview

Sorry, preview is currently unavailable. You can download the paper by clicking the button above.

References (156)

  1. Tillett CW. Posterior lamellar keratoplasty. Am J Ophthal- mol 1956;41:530 -3.
  2. Polack FM. Posterior lamellar keratoplasty [in Spanish]. Rev Peru Oftalmol 1965;2:62-4.
  3. Melles GR, Eggink FA, Lander F, et al. A surgical technique for posterior lamellar keratoplasty. Cornea 1998;17:618 -26.
  4. Melles GR, Lander F, Beekhuis WH, et al. Posterior lamellar keratoplasty for a case of pseudophakic bullous keratopathy. Am J Ophthalmol 1999;127:340 -1.
  5. Azar DT, Jain S, Sambursky R, Strauss L. Microkeratome- assisted posterior keratoplasty. J Cataract Refract Surg 2001; 27:353-6.
  6. Busin M, Arffa RC, Sebastiani A. Endokeratoplasty as an alternative to penetrating keratoplasty for the surgical treat- ment of diseased endothelium: initial results. Ophthalmology 2000;107:2077-82.
  7. Ehlers N, Ehlers H, Hjortdal J, Moller-Pedersen T. Grafting of the posterior cornea. Description of a new technique with 12- month clinical results. Acta Ophthalmol Scand 2000;78:543-6.
  8. Li L, Ellis KR, Behrens A, al. A laboratory model for microkeratome-assisted posterior lamellar keratoplasty uti- lizing a running graft suture and a sutureless hinged flap. Cornea 2002;21:192-5.
  9. Terry MA. Endothelial keratoplasty: clinical outcomes in the two years following deep lamellar endothelial keratoplasty (an American Ophthalmological Society thesis). Trans Am Ophthalmol Soc 2007;105:530 -63.
  10. Terry MA, Ousley PJ. Deep lamellar endothelial keratoplasty in the first United States patients: early clinical results. Cor- nea 2001;20:239 -43.
  11. Terry MA, Ousley PJ. Endothelial replacement without surface corneal incisions or sutures: topography of the deep lamellar endothelial keratoplasty procedure. Cornea 2001;20:14 -8.
  12. Terry MA, Ousley PJ. Replacing the endothelium without corneal surface incisions or sutures: the first United States clinical series using the deep lamellar endothelial kerato- plasty procedure. Ophthalmology 2003;110:755-64.
  13. Melles GR, Wijdh RH, Nieuwendaal CP. A technique to excise the Descemet membrane from a recipient cornea (de- scemetorhexis). Cornea 2004;23:286 -8.
  14. Price FW Jr, Price MO. Descemet's stripping with endothe- lial keratoplasty in 50 eyes: a refractive neutral corneal transplant. J Refract Surg 2005;21:339 -45.
  15. Price FW Jr, Price MO. Descemet's stripping with endothe- lial keratoplasty in 200 eyes: early challenges and techniques to enhance donor adherence. J Cataract Refract Surg 2006; 32:411-8.
  16. Gorovoy MS. Descemet-stripping automated endothelial ker- atoplasty. Cornea 2006;25:886 -9.
  17. Aralikatti A, Dean S, Busin M, Shah S. Pull-through tech- nique for graft insertion in DSAEK [letter]. J Cataract Re- fract Surg 2008;34:341; author reply 41-2.
  18. Armour RL, Ousley PJ, Wall J, et al. Endothelial kerato- plasty using donor tissue not suitable for full-thickness pen- etrating keratoplasty. Cornea 2007;26:515-9.
  19. Bahar I, Kaiserman I, Buys Y, Rootman D. Descemet's strip- ping with endothelial keratoplasty in iridocorneal endothelial syndrome. Ophthalmic Surg Lasers Imaging 2008;39:54 -6.
  20. Bradley JC, McCartney DL. Descemet's stripping auto- mated endothelial keratoplasty in intraoperative floppy- iris syndrome: suture-drag technique. J Cataract Refract Surg 2007;33:1149-50.
  21. Busin M, Bhatt PR. Late detachment of donor graft after Descemet stripping automated endothelial keratoplasty. J Cataract Refract Surg 2008;34:159 -60.
  22. Chen ES, Shamie N, Terry MA. Endothelial keratoplasty: first report of a ruptured globe after deep lamellar endothelial keratoplasty. Cornea 2007;26:874 -5.
  23. Chen ES, Shamie N, Terry MA. Descemet-stripping endo- thelial keratoplasty: improvement in vision following re- placement of a healthy endothelial graft. J Cataract Refract Surg 2008;34:1044 -6.
  24. Chen ES, Shamie N, Terry MA, Hoar KL. Endothelial keratoplasty: improvement of vision after healthy donor tis- sue exchange. Cornea 2008;27:279 -82.
  25. Duarte MC, Herndon LW, Gupta PK, Afshari NA. DSEK in eyes with double glaucoma tubes [letter]. Ophthalmology 2008;115:1435.
  26. Dupps WJ Jr, Qian Y, Meisler DM. Multivariate model of refractive shift in Descemet-stripping automated endothelial keratoplasty. J Cataract Refract Surg 2008;34:578 -84.
  27. Fang JP, Hamill MB. Descemet's stripping endothelial ker- atoplasty under topical anesthesia. J Cataract Refract Surg 2007;33:187-8.
  28. Fernandez MM, Buckley EG, Afshari NA. Descemet strip- ping automated endothelial keratoplasty in a child. J AAPOS 2008;12:314 -6.
  29. Gorovoy MS. Precut tissue for Descemet stripping auto- mated endothelial keratoplasty. Cornea 2008;27:632-3.
  30. Gorovoy MS, Meisler DM, Dupps WJ Jr. Late repeat De- scemet-stripping automated endothelial keratoplasty. Cornea 2008;27:238 -40.
  31. Habib NE, Gomaa A. Suture-pull technique for insertion of donor lenticule in endothelial keratoplasty [letter]. Cornea 2008;27:1098 -9.
  32. Harvey TM. Small incision insertion of posterior lamellar button [letter].
  33. J Refract Surg 2006;22:429.
  34. Holz HA, Meyer JJ, Espandar L, et al. Corneal profile anal- ysis after Descemet stripping endothelial keratoplasty and its relationship to postoperative hyperopic shift. J Cataract Re- fract Surg 2008;34:211-4.
  35. Inoue T, Oshima Y, Shima C, et al. Chandelier illumination to complete Descemet stripping through severe hazy cornea during Descemet-stripping automated endothelial kerato- plasty. J Cataract Refract Surg 2008;34:892-6.
  36. Jeng BH, Marcotty A, Traboulsi EI. Descemet stripping automated endothelial keratoplasty in a 2-year-old child. J AAPOS 2008;12:317-8.
  37. Jhanji V, Greenrod E, Sharma N, Vajpayee RB. Modifications in the surgical technique of Descemet stripping automated en- dothelial keratoplasty. Br J Ophthalmol 2008;92:1311-68.
  38. Jhanji V, Greenrod E, Vajpayee RB. Donor dislocation after DSAEK for a failed corneal graft. Br J Ophthalmol 2008;92: 1185-292.
  39. Koenig SB, Covert DJ. Epithelial ingrowth after Descemet- stripping automated endothelial keratoplasty. Cornea 2008; 27:727-9.
  40. Koenig SB, Dupps WJ Jr, Covert DJ, Meisler DM. Simple technique to unfold the donor corneal lenticule during De- scemet's stripping and automated endothelial keratoplasty. J Cataract Refract Surg 2007;33:189 -90.
  41. Kymionis GD, Suh LH, Dubovy SR, Yoo SH. Diagnosis of residual Descemet's membrane after Descemet's stripping endothelial keratoplasty with anterior segment optical coher- ence tomography. J Cataract Refract Surg 2007;33:1322-4.
  42. Lake DB, Rostron CK. Management of angle-supported in- traocular lens and iridectomy in Descemet-stripping endo- thelial keratoplasty. Cornea 2008;27:223-24.
  43. Leyland M. Anterior chamber maintenance during Descemet stripping [letter]. Cornea 2007;26:1292-3; author reply 93.
  44. Macaluso C. Closed-chamber pulling-injection system for donor graft insertion in endothelial keratoplasty. J Cataract Refract Surg 2008;34:353-6.
  45. Macsai MS. Advantages of suture-pull technique for De- scemet's stripping and endothelial keratoplasty [letter]. Cor- nea 2008;27:1099 -100.
  46. Macsai MS, Kara-Jose AC. Suture technique for Descemet stripping and endothelial keratoplasty. Cornea 2007;26:1123-6.
  47. Mehta JS, Poh R, Beuerman RW, Tan DT. Late endothelial failure after Descemet stripping automated endothelial kera- toplasty [letter]. Cornea 2008;27:1215-6; author reply 16.
  48. Mehta JS, Por YM, Beuerman RW, Tan DT. Glide insertion technique for donor cornea lenticule during Descemet's strip- ping automated endothelial keratoplasty. J Cataract Refract Surg 2007;33:1846 -50.
  49. Mehta JS, Thomas AS, Tan DT. Endothelial keratoplasty [letter]. Ophthalmology 2008;115:420; author reply 20 -1.
  50. Meisler DM, Dupps WJ Jr, Covert DJ, Koenig SB. Use of an air-fluid exchange system to promote graft adhesion during Descemet's stripping automated endothelial keratoplasty. J Cataract Surg 2007;33:770 -2.
  51. Melles GR. Posterior lamellar keratoplasty: DLEK to DSEK to DMEK. Cornea 2006;25:879 -81.
  52. Prakash G, Jhanji V, Titiyal JS. Will Descemet's stripping with automated endothelial keratoplasty (DSAEK) lower the rates of allograft rejection in corneal transplants for endothe- lial failure? Med Hypotheses 2007;69:1117-9.
  53. Price FW Jr. Precut tissue for Descemet stripping automated endothelial keratoplasty. Cornea 2008;27:630 -1.
  54. Price FW Jr, Price MO. A nonsurgical treatment for donor dislocation after Descemet stripping endothelial keratoplasty (DSEK) [letter]. Cornea 2006;25:991.
  55. Price FW Jr, Price MO. Endothelial keratoplasty to restore clarity to a failed penetrating graft. Cornea 2006;25:895-9.
  56. Price MO, Price FW Jr. Descemet stripping with endothelial keratoplasty for treatment of iridocorneal endothelial syn- drome. Cornea 2007;26:493-7.
  57. Price MO, Price FW Jr, Stoeger C, et al. Central thickness variation in precut DSAEK donor grafts [letter]. J Cataract Refract Surg 2008;34:1423-4.
  58. Price MO, Price FW Jr, Trespalacios R. Endothelial kerato- plasty technique for aniridic aphakic eyes. J Cataract Refract Surg 2007;33:376 -9.
  59. Rao SK, Leung CK, Cheung CY, et al. Descemet stripping endothelial keratoplasty: effect of the surgical procedure on corneal optics. Am J Ophthalmol 2008;145:991-6.
  60. Romaniv N, Price MO, Price FW, Mamalis N. Donor De- scemet membrane detachment after endothelial keratoplasty. Cornea 2006;25:943-7.
  61. Steinert RF. Posterior lamellar endothelial keratoplasty: cor- neal transplantation and refractive surgery intersect. Arch Ophthalmol 2008;126:263-4.
  62. Suh LH, Kymionis GD, Culbertson WW, et al. Descemet stripping with endothelial keratoplasty in aphakic eyes. Arch Ophthalmol 2008;126:268 -70.
  63. Tay E, Rajan MS, Saw VP, Dart JK. Dislocated intraocular lens into the vitreous cavity after DSAEK [letter]. J Cataract Refract Surg 2008;34:525-6.
  64. Terry MA. Endothelial keratoplasty: history, current state, and future directions. Cornea 2006;25:873-8.
  65. Terry MA. Precut tissue for Descemet stripping automated endothelial keratoplasty: complications are from technique, not tissue. Cornea 2008;27:627-9.
  66. Vajaranant TS, Price MO, Price FW, et al. Intraocular pres- sure measurements following Descemet stripping endothelial keratoplasty. Am J Ophthalmol 2008;145:780 -6.
  67. Vajpayee RB, Agarwal T, Jhanji V, Sharma N. Modification in Descemet-stripping automated endothelial keratoplasty: "hitch suture" technique. Cornea 2006;25:1060 -2.
  68. van Dooren BT, Mulder PG, Nieuwendaal CP, et al. Endo- thelial cell density after posterior lamellar keratoplasty: five- to seven-year follow-up. Am J Ophthalmol 2007;144:471-3.
  69. van Rij G, Bartels M, Pels L. Posterior lamellar keratoplasty [letter]. Cornea 2007;26:1024; author reply 24.
  70. Walker BM, Hindman HB, Ebrahimi KB, et al. Epithelial downgrowth following Descemet's-stripping automated endo- thelial keratoplasty [letter]. Arch Ophthalmol 2008;126:278-80.
  71. Culbertson WW. Descemet stripping endothelial kerato- plasty. Int Ophthalmol Clin 2006;46(3 Summer):155-68.
  72. Goins KM. Surgical alternatives to penetrating keratoplasty II: endothelial keratoplasty. Int Ophthalmol 2008;28:233-46.
  73. Price MO, Price FW. Descemet's stripping endothelial ker- atoplasty. Curr Opin Ophthalmol 2007;18:290 -4.
  74. Tan DT, Mehta JS. Future directions in lamellar corneal transplantation. Cornea 2007;26(suppl):S21-8.
  75. Heindl LM, Hofmann-Rummelt C, Schlotzer-Schrehardt U, et al. Histologic analysis of Descemet stripping in posterior lamellar keratoplasty. Arch Ophthalmol 2008;126:461-4.
  76. Ide T, Yoo SH, Goldman JM, et al. Descemet-stripping auto- mated endothelial keratoplasty: effect of inserting forceps on DSAEK donor tissue viability by using an in vitro delivery model and vital dye assay. Cornea 2007;26:1079 -81.
  77. Ide T, Yoo SH, Kymionis GD, et al. Descemet-stripping automated endothelial keratoplasty: effect of anterior lamel- lar corneal tissue-on/-off storage condition on Descemet- stripping automated endothelial keratoplasty donor tissue. Cornea 2008;27:754 -7.
  78. Ide T, Yoo SH, Kymionis GD, et al. Descemet-stripping automated endothelial keratoplasty (DSAEK): effect of non- toxic gentian violet marking pen on DSAEK donor tissue viability by using vital dye assay. Cornea 2008;27:562-4.
  79. Kobayashi A, Mawatari Y, Yokogawa H, Sugiyama K. In vivo laser confocal microscopy after Descemet stripping with automated endothelial keratoplasty. Am J Ophthalmol 2008; 145:977-85.
  80. Kuo AN, Harvey TM, Afshari NA. Novel delivery method to reduce endothelial injury in Descemet stripping automated endothelial keratoplasty. Am J Ophthalmol 2008;145:91-6.
  81. Lord RK, Price FW, Price MO, et al. Histology of posterior lamellar keratoplasty. Cornea 2006;25:1093-6.
  82. Mehta JS, Chua J, Poh R, et al. Primary graft failure after Descemet-stripping automated endothelial keratoplasty: clinico-pathological study. Cornea 2008;27:722-6.
  83. Mondloch MC, Giegengack M, Terry MA, Wilson DJ. His- tologic evidence of retained fetal layer of the Descemet membrane after presumed total removal for endothelial keratoplasty: a possible cause for graft failure. Cornea 2007; 26:1263-6.
  84. Oster SF, Ebrahimi KB, Eberhart CG, et al. A clinicopatho- logic series of primary graft failure after Descemet's strip- ping and automated endothelial keratoplasty. Ophthalmology 2009;116:609 -14.
  85. Rose L, Briceno CA, Stark WJ, et al. Assessment of eye bank-prepared posterior lamellar corneal tissue for endothe- lial keratoplasty. Ophthalmology 2008;115:279 -86.
  86. Saad HA, Terry MA, Shamie N, et al. An easy and inexpen- sive method for quantitative analysis of endothelial damage by using vital dye staining and Adobe Photoshop software. Cornea 2008;27:818 -24.
  87. Sbarbaro JA, Eagle RC, Thumma P, Raber IM. Histopathol- ogy of posterior lamellar endothelial keratoplasty graft fail- ure. Cornea 2008;27:900 -4.
  88. Terry MA, Hoar KL, Wall J, Ousley P. Histology of dislo- cations in endothelial keratoplasty (DSEK and DLEK): a laboratory-based, surgical solution to dislocation in 100 con- secutive DSEK cases. Cornea 2006;25:926 -32.
  89. Price MO, Baig KM, Brubaker JW, Price FW Jr. Random- ized, prospective comparison of precut vs surgeon-dissected grafts for Descemet stripping automated endothelial kerato- plasty. Am J Ophthalmol 2008;146:36 -41.
  90. Bahar I, Kaiserman I, McAllum P, et al. Comparison of posterior lamellar keratoplasty techniques to penetrating ker- atoplasty. Ophthalmology 2008;115:1525-33.
  91. Bahar I, Kaiserman I, Sansanayudh W, et al. Busin guide vs forceps for the insertion of the donor lenticule in Descemet stripping automated endothelial keratoplasty. Am J Ophthal- mol 2009;147:220 -26.
  92. Bahar I, Sansanayudh W, Levinger E, et al. Posterior lamel- lar keratoplasty-comparison of deep lamellar endothelial keratoplasty and Descemet stripping automated endothelial keratoplasty in the same patients: a patient's Br J Ophthalmol 2009;93:186 -90.
  93. Basak SK. Descemet stripping and endothelial keratoplasty in endothelial dysfunctions: three-month results in 75 eyes. Indian J Ophthalmol 2008;56:291-6.
  94. Busin M, Bhatt PR, Scorcia V. A modified technique for Descemet membrane stripping automated endothelial kera- toplasty to minimize endothelial cell loss. Arch Ophthalmol 2008;126:1133-7.
  95. Chen ES, Terry MA, Shamie N, et al. Descemet-stripping automated endothelial keratoplasty: six-month results in a prospective study of 100 eyes. Cornea 2008;27:514 -20.
  96. Chen ES, Terry MA, Shamie N, et al. Precut tissue in Descemet's stripping automated endothelial keratoplasty: donor characteristics and early postoperative complications. Ophthalmology 2008;115:497-502.
  97. Covert DJ, Koenig SB. Descemet stripping and automated endothelial keratoplasty (DSAEK) in eyes with failed pene- trating keratoplasty. Cornea 2007;26:692-6.
  98. Covert DJ, Koenig SB. New triple procedure: Descemet's stripping and automated endothelial keratoplasty combined with phacoemulsification and intraocular lens implantation. Ophthalmology 2007;114:1272-7.
  99. Kaiserman I, Bahar I, McAllum P, et al. Suture-assisted vs forceps-assisted insertion of the donor lenticula during De- scemet stripping automated endothelial keratoplasty. Am J Ophthalmol 2008;145:986 -90.
  100. Kobayashi A, Yokogawa H, Sugiyama K. Descemet stripping with automated endothelial keratoplasty for bullous keratopa- thies secondary to argon laser iridotomy-preliminary results and usefulness of double-glide donor insertion technique. Cor- nea 2008;27(suppl):S62-9.
  101. Koenig SB, Covert DJ. Early results of small-incision De- scemet's stripping and automated endothelial keratoplasty. Ophthalmology 2007;114:221-6.
  102. Koenig SB, Covert DJ, Dupps WJ Jr, Meisler DM. Visual acuity, refractive error, and endothelial cell density six months after Descemet stripping and automated endothelial keratoplasty (DSAEK). Cornea 2007;26:670 -4.
  103. Mearza AA, Qureshi MA, Rostron CK. Experience and 12-month results of Descemet-stripping endothelial kerato- plasty (DSEK) with a small-incision technique. Cornea 2007; 26:279 -83.
  104. Mehta JS, Por YM, Poh R, et al. Comparison of donor insertion techniques for Descemet stripping automated endo- thelial keratoplasty. Arch Ophthalmol 2008;126:1383-8.
  105. O'Brien PD, Lake DB, Saw VP, et al. Endothelial keratoplasty: case selection in the learning curve. Cornea 2008;27:1114 -8.
  106. Price MO, Price FW Jr. Descemet's stripping with endothelial keratoplasty: comparative outcomes with microkeratome- dissected and manually dissected donor tissue. Ophthalmol- ogy 2006;113:1936 -42.
  107. Price MO, Price FW Jr. Endothelial cell loss after Descemet stripping with endothelial keratoplasty: influencing factors and 2-year trend. Ophthalmology 2008;115:857-65.
  108. Sarnicola V, Toro P. Descemet-stripping automated endothe- lial keratoplasty by using suture for donor insertion. Cornea 2008;27:825-9.
  109. Suh LH, Yoo SH, Deobhakta A, et al. Complications of De- scemet's stripping with automated endothelial keratoplasty: sur- vey of 118 eyes at one institute. Ophthalmology 2008;115: 1517-24.
  110. Terry MA, Chen ES, Shamie N, et al. Endothelial cell loss after Descemet's stripping endothelial keratoplasty in a large prospective series. Ophthalmology 2008;115:488 -96.
  111. Terry MA, Shamie N, Chen ES, et al. Endothelial keratoplasty: a simplified technique to minimize graft dislocation, iatrogenic graft failure, and pupillary block. Ophthalmology 2008; 115:1179 -86.
  112. Terry MA, Shamie N, Chen ES, et al. Endothelial keratoplasty: the influence of preoperative donor endothelial cell densities on dislocation, primary graft failure, and 1-year cell counts. Cornea 2008;27:1131-7.
  113. Terry MA, Shamie N, Chen ES, et al. Precut tissue for Descemet's stripping automated endothelial keratoplasty: vi- sion, astigmatism, and endothelial survival. Ophthalmology 2009;116:248 -56.
  114. Terry MA, Shamie N, Chen ES, et al. Endothelial kerato- plasty for Fuchs' dystrophy with cataract: complications and clinical results with the new triple procedure. Ophthalmology 2009;116:631-9.
  115. Wylegala E, Tarnawska D. Management of pseudophakic bullous keratopathy by combined Descemet-stripping endo- thelial keratoplasty and intraocular lens exchange. J Cataract Refract Surg 2008;34:1708 -14.
  116. Yoo SH, Kymionis GD, Deobhakta AA, et al. One-year results and anterior segment optical coherence tomography findings of Descemet stripping automated endothelial kera- toplasty combined with phacoemulsification. Arch Ophthal- mol 2008;126:1052-5.
  117. Allan BD, Terry MA, Price FW Jr, et al. Corneal transplant rejection rate and severity after endothelial keratoplasty. Cor- nea 2007;26:1039 -42.
  118. Jordan CS, Price MO, Trespalacios R, Price FW Jr. Graft rejection episodes after Descemet stripping with endothelial keratoplasty. Part one: clinical signs and symptoms. Br J Ophthalmol 2009;93:387-90.
  119. Jun B, Kuo AN, Afshari NA, et al. Refractive change after Descemet stripping automated endothelial keratoplasty surgery and its correlation with graft thickness and diameter. Cornea 2009;28:19 -23.
  120. Bertelmann E, Pleyer U, Rieck P. Risk factors for endothelial cell loss post-keratoplasty. Acta Ophthalmol Scand 2006;84: 766 -70.
  121. Bourne WM. One-year observation of transplanted human corneal endothelium. Ophthalmology 1980;87:673-9.
  122. Bourne WM, Nelson LR, Maguire LJ, et al. Comparison of Chen Medium and Optisol-GS for human corneal preservation at 4 degrees C: results of transplantation. Cornea 2001;20: 683-6.
  123. Culbertson WW, Abbott RL, Forster RK. Endothelial cell loss in penetrating keratoplasty. Ophthalmology 1982;89: 600 -4.
  124. Frueh BE, Bohnke M. Prospective, randomized clinical eval- uation of Optisol vs organ culture corneal storage media. Arch Ophthalmol 2000;118:757-60.
  125. Lass JH, Bourne WM, Musch DC, et al. A randomized, pro- spective, double-masked clinical trial of Optisol vs Dexsol cor- neal storage media. Arch Ophthalmol 1992;110:1404 -8.
  126. Patel SV, Hodge DO, Bourne WM. Corneal endothelium and postoperative outcomes 15 years after penetrating keratoplasty. Trans Am Ophthalmol Soc 2004;102:57-65; discussion 65-6.
  127. Lee WB, Mannis MJ. Corneal suturing techniques. In: Macsai MS, ed. Ophthalmic Microsurgical Suturing Techniques. Berlin: Springer, 2007:49 -60.
  128. Verdier DD. Penetrating keratoplasty. In: Krachmer JH, Mannis MJ, Holland EJ, eds. Cornea. v. 2. Surgery of the Cornea and Conjunctiva. 2nd ed. Philadelphia: Elsevier Mosby, 2005:1441-52.
  129. Speaker MG, Haq F, Latkany R, Reing CS. Postkeratoplasty astigmatism. In: Krachmer JH, Mannis MJ, Holland EJ, eds.
  130. Cornea. v. 2. Surgery of the Cornea and Conjunctiva. 2nd ed. Philadelphia: Elsevier Mosby, 2005:1527-40.
  131. Nagra PK, Hammersmith KM, Rapuano CJ, et al. Wound dehiscence after penetrating keratoplasty. Cornea 2006;25: 132-5.
  132. Renucci AM, Marangon FB, Culbertson WW. Wound dehis- cence after penetrating keratoplasty: clinical characteristics of 51 cases treated at Bascom Palmer Eye Institute. Cornea 2006;25:524 -9.
  133. Tran TH, Ellies P, Azan F, et al. Traumatic globe rupture following penetrating keratoplasty. Graefes Arch Clin Exp Ophthalmol 2005;243:525-30.
  134. Tseng SH, Lin SC, Chen FK. Traumatic wound dehiscence after penetrating keratoplasty: clinical features and outcome in 21 cases. Cornea 1999;18:553-8.
  135. Williams MA, Gawley SD, Jackson AJ, Frazer DG. Trau- matic graft dehiscence after penetrating keratoplasty. Oph- thalmology 2008;115:276 -78 e1.
  136. Abou-Jaoude ES, Brooks M, Katz DG, Van Meter WS. Spontaneous wound dehiscence after removal of single con- tinuous penetrating keratoplasty suture. Ophthalmology 2002;109:1291-6; discussion 1297.
  137. Ugarte M, Falcon MG. Spontaneous wound dehiscence after removal of single continuous penetrating kerato- plasty suture: conservative management. Cornea 2006;25: 1260 -1.
  138. Christo CG, van Rooij J, Geerards AJ, et al. Suture-related complications following keratoplasty: a 5-year retrospective study. Cornea 2001;20:816 -9.
  139. Ingraham HJ, Donnenfeld ED, Perry HD. Massive supracho- roidal hemorrhage in penetrating keratoplasty. Am J Oph- thalmol 1989;108:670 -5.
  140. Price FW Jr, Whitson WE, Ahad KA, Tavakkoli H. Supra- choroidal hemorrhage in penetrating keratoplasty. Ophthal- mic Surg 1994;25:521-5.
  141. Purcell JJ Jr, Krachmer JH, Doughman DJ, Bourne WM. Expulsive hemorrhage in penetrating keratoplasty. Ophthal- mology 1982;89:41-3.
  142. van Rensburg PD, Raber IM, Laibson PR, Eagle RC Jr. Management of primary corneal graft failure. Cornea 1998; 17:208 -11.
  143. Mead MD, Hyman L, Grimson R, Schein OD. Primary graft failure: a case control investigation of a purported cluster. Cornea 1994;13:310 -6.
  144. Wilhelmus KR, Stulting RD, Sugar J, Khan MM, Medical Advisory Board of the Eye Bank Association of America. Primary corneal graft failure: a national reporting system. Arch Ophthalmol 1995;113:1497-502.
  145. de Freitas AM, Melo BC, Mendonca CN, et al. Causes and risk factors for graft failure in surgeries performed by phy- sicians in fellowship training. Cornea 2006;25:251-6.
  146. Lass JH, Gal RL, Dontchev M, et al. Donor age and corneal endothelial cell loss 5 years after successful corneal trans- plantation. Specular microscopy ancillary study results. Oph- thalmology 2008;115:627-32 e8.
  147. Cornea Donor Study Investigator Group. The effect of donor age on corneal transplantation outcome: results of the Cornea Donor Study. Ophthalmology 2008;115:620 -6.
  148. Claesson M, Armitage WJ, Fagerholm P, Stenevi U. Visual outcome in corneal grafts: a preliminary analysis of the Swedish Corneal Transplant Register. Br J Ophthalmol 2002; 86:174 -80.
  149. Thompson RW Jr, Price MO, Bowers PJ, Price FW Jr. Long-term graft survival after penetrating keratoplasty. Oph- thalmology 2003;110:1396 -402.
  150. Guerin M, O'Connell E, Walsh C, Fulcher T. Visual out- comes and graft survival following corneal transplants: the need for an Irish National Corneal Transplant Registry. Ir J Med Sci 2008;177:107-10.
  151. Footnotes and Financial Disclosures Originally received: April 28, 2009. Accepted: June 10, 2009. Available online: July 30, 2009. Manuscript no. 2009-579.
  152. Prepared by the Ophthalmic Technology Assessment Committee Cornea and Anterior Segment Disorders Panel and approved by the American Academy of Ophthalmology's Board of Trustees February 21, 2009. Financial Disclosure(s): The author(s) have made the following disclosure(s): W. Barry Lee -Consultant -Allergan, Inc.; Lecture Fees -Allergan, Inc., Bausch & Lomb Surgical, Inspire
  153. Deborah S. Jacobs -Employee -The Boston Foundation for Sight 501(c)3
  154. David C. Musch -Consultant -Glaukos Corporation, MacuSight, Inc., NeoVista, Inc., Neurotech USA, Inc., Oraya Therapeutics, Inc.; Grant Support -Midwest EyeBanks, National Eye Institute, Washington Univer- sity;
  155. Pfizer, Recipient of Research to Prevent Blindness Lew R. Wasserman Merit Award.
  156. Stephen C. Kaufman -Lecture Fees -Alcon Laboratories, Inc., Allergan, Inc. Funded without commercial support by the American Academy of Ophthalmology. Correspondence: W. Barry Lee, MD, 3225 Cumberland Boulevard, Suite 900, Eye Consult- ants of Atlanta, Atlanta, GA 30339. E-mail: lee0003@aol.com.