Transgenic overexpression of the sarcoplasmic reticulum Ca2+ATPase improves reticular Ca2+ handling in normal and diabetic rat hearts (original) (raw)
Replacement of the Muscle-Specific Sarcoplasmic Reticulum Ca2+-ATPase Isoform SERCA2a by the Nonmuscle SERCA2b Homologue Causes Mild Concentric Hypertrophy and Impairs Contraction-Relaxation of the Heart
Jean Lebacq
Circulation Research, 2001
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Christine Misquitta
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Overexpression of SERCA2b in the Heart Leads to an Increase in Sarcoplasmic Reticulum Calcium Transport Function and Increased Cardiac Contractility
Irene Adler
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Replacement of the Muscle-Specific Sarcoplasmic Reticulum Ca21ATPase Isoform SERCA2a by the Nonmuscle SERCA2b Homologue Causes Mild Concentric Hypertrophy and Impairs Contraction-Relaxation of the Heart
Jean Lebacq
2000
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Improvement in Survival and Cardiac Metabolism After Gene Transfer of Sarcoplasmic Reticulum Ca21ATPase in a Rat Model of Heart Failure
ulrich Schmidt
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Serine Phosphorylation of the Sarcoplasmic Reticulum Ca2+-ATPase in the Intact Beating Rabbit Heart
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Increased SR Ca2+ cycling contributes to improved contractile performance in SERCA2a-overexpressing transgenic rats
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Defective intracellular Ca 2+ signaling contributes to cardiomyopathy in Type 1 diabetic rats
Silvia Guatimosim
American Journal of Physiology - Heart and Circulatory Physiology, 2002
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Sarco/endoplasmic reticulum calcium ATPase activity is unchanged despite increased myofilament calcium sensitivity in Zucker type 2 diabetic fatty rat heart
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Sarco(endo)plasmic reticulum Ca2+ ATPase (SERCA) gene silencing and remodeling of the Ca2+ signaling mechanism in cardiac myocytes
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Comparison of Ca2+release and uptake characteristics of the sarcoplasmic reticulum in isolated horse and rabbit cardiomyocytes
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American Journal of Physiology-Heart and Circulatory Physiology, 2004
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Targeted Overexpression of Sarcolipin in the Mouse Heart Decreases Sarcoplasmic Reticulum Calcium Transport and Cardiac Contractility
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Sarco (Endo) Plasmic Reticulum Calcium Atpases (SERCA) Isoforms in the Normal and Diseased Cardiac, Vascular and Skeletal Muscle
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Improvement in Survival and Cardiac Metabolism After Gene Transfer of Sarcoplasmic Reticulum Ca2+-ATPase in a Rat Model of Heart Failure
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The nature of the modulation of Ca2+ transport as studied by reconstitution of cardiac sarcoplasmic reticulum
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Ca2+ transport ATPase isoforms SERCA2a and SERCA2b are targeted to the same sites in the murine heart
William Louch
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Impaired sarcoplasmic reticulum function leads to contractile dysfunction and cardiac hypertrophy
Harm Knot
American Journal of Physiology-Heart and Circulatory Physiology, 2001
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Unbalance Between Sarcoplasmic Reticulum Ca2 + Uptake and Release: A First Step Toward Ca2 + Triggered Arrhythmias and Cardiac Damage
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Impaired Cardiac Performance in Heterozygous Mice with a Null Mutation in the Sarco(endo)plasmic Reticulum Ca2+-ATPase Isoform 2 (SERCA2) Gene
Thomas Reed
Journal of Biological Chemistry, 1999
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Shortening and intracellular Ca2+ in ventricular myocytes and expression of genes encoding cardiac muscle proteins in early onset type 2 diabetic Goto-Kakizaki rats
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