Comparison of Paraoxonase 1 Measurements in Serum and in Lithium-Heparin-Anticoagulated Plasma Samples (original) (raw)
Comparison of Paraoxonase 1 Measurements in Serum and in Lithium-Heparin-Anticoagulated Plasma Samples
Clinical Chemistry, 2005
Abstract
Serum is the preferred sample for PON1 measurement because this enzyme requires calcium for both activity and stability. The presence of calcium chelators such as EDTA or citrate as anticoagulants inhibits PON1 activity (3). This is a serious limitation in retrospective studies, in which ...
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