DRUGS IN INFANTS AND CHILDRENS (original) (raw)

Pharmacokinetic studies in children: recommendations for practice and research

Allison Needham

Archives of Disease in Childhood, 2018

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Pharmacokinetic predictions in children by using the physiologically based pharmacokinetic modelling

francois bouzom

Fundamental & Clinical Pharmacology, 2008

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Pediatric pharmacology: current efforts and future goals to improve clinical practice

Elke Krekels

Expert Opinion on Drug Metabolism & Toxicology, 2015

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General clinical and methodological considerations on the extrapolation of pharmacokinetics and optimization of study protocols for small molecules and monoclonal antibodies in children

Anna-Karin Hamberg

British Journal of Clinical Pharmacology

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How to optimise drug study design: pharmacokinetics and pharmacodynamics studies introduced to paediatricians

Eric Vermeulen

Journal of Pharmacy and Pharmacology

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A pharmacokinetic standard for babies and adults

Nick Holford

Journal of Pharmaceutical Sciences, 2013

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Overview of Clinical Pharmacokinetics in Pediatrics: Possible Implications in Therapy

Herbert Obu

Biomedical & Pharmacology Journal, 2014

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Dosing in children

Nick Holford

Clinical Pharmacology and Therapeutics, 2010

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‘Formulating better medicines for children’ – The leap forward

Smita Salunke

International Journal of Pharmaceutics, 2014

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Design and conduct of early phase drug studies in children: challenges and opportunities

Michael Rieder

British Journal of Clinical Pharmacology, 2016

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Paediatric Pharmacotherapy and Drug Regulation -- Moving Past the Therapeutic Orphan

Michael Rieder

2020

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Evaluation of Child/Adult Pharmacokinetic Differences from a Database Derived from the Therapeutic Drug Literature

Dale Hattis, Rob Goble

Toxicological Sciences, 2002

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Drug Development for Pediatric Populations: Regulatory Aspects

Jasper Dingemanse

Pharmaceutics, 2010

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Newborns, Older Children, and Adults Comparisons of Pharmacokinetics and Pharmacokinetic Variability

Rob Goble

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Committee for Medicinal Products for Human Use (CHMP) 3 Paediatric Committee (PDCO) 4 Guideline on pharmaceutical development of medicines 5 for paediatric use

Keith Benson

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Perspectives on Pediatric Drug Development

Gregory Knipp

Revista Mexicana De Ciencias Farmaceuticas, 2012

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The development of medicines for children

Paolo Tomasi

Pharmacological Research, 2011

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Safety of new medicines in young children

Imti Choonara

Archives of Disease in Childhood, 2011

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European Paediatric Formulation Initiative (EuPFI)—Formulating Ideas for Better Medicines for Children

Smita Salunke

AAPS PharmSciTech, 2016

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Frameworks for Evaluating Medicines in Children

Steven Hirschfeld

Clinical therapeutics, 2017

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What is the right dose for children?

Meindert Danhof

British Journal of Clinical Pharmacology, 2010

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Formulating Medicines for Children : Challenges and Issues

Cosimo Altomare

2016

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Pediatric Formulations: Knowledge Gaps Limiting the Expedited Preclinical to Clinical Translation in Children

Gregory Knipp

Aaps Pharmscitech, 2019

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Advances in Pediatric Pharmacology, Therapeutics, and Toxicology

Daniel Gonzalez

Advances in Pediatrics, 2014

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European Paediatric Formulation Initiative's (EuPFI) 2nd conference commentary—Formulating better medicines for children

Smita Salunke

International Journal of Pharmaceutics, 2011

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Paediatric clinical pharmacology in the UK

Imti Choonara

Archives of Disease in Childhood, 2014

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Improving Predictive Modeling in Pediatric Drug Development: Pharmacokinetics, Pharmacodynamics, and Mechanistic Modeling

David Dorman

Annals of the New York Academy of Sciences, 2005

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Approaches to Dose Finding in Neonates, Illustrating the Variability between Neonatal Drug Development Programs

Ramy Abdelrahman

Pharmaceutics, 2020

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Biopharmaceutical considerations in paediatrics with a view to the evaluation of orally administered drug products – a PEARRL review

Maria Vertzoni

Journal of Pharmacy and Pharmacology, 2018

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Challenges in pediatric drug use: A pharmacist point of view

Vivienne Mak

Research in Social & Administrative Pharmacy, 2017

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Paediatric Drug Development and Formulation Design-a European Perspective

Brian Aylward

AAPS PharmSciTech, 2016

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Dosing information in a standard drug reference: Are pediatrics still therapeutically neglected?

Asrul Shafie, Mohamed Azmi Hassali

Pediatrics International, 2010

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Off-label drug use in pediatric patients

E. Kimland

Clinical pharmacology and therapeutics, 2012

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