The BK channel: a vital link between cellular calcium and electrical signaling (original) (raw)

Molecular mechanisms of BK channel activation

Huanghe Yang

Cellular and molecular life sciences, 2009

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Ca2+- and Voltage-Activated K+ (BK) Channels in the Nervous System: One Gene, a Myriad of Physiological Functions

Ramon Latorre

International Journal of Molecular Sciences

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Structural Determinants for Functional Coupling Between the and Subunits in the Ca2+-activated K+ (BK) Channel

Patricio Orio

The Journal of General Physiology, 2006

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Molecular basis of fast inactivation in voltage and Ca 2+ -activated K + channels: A transmembrane β-subunit homolog

Meera Pratap

Proceedings of the National Academy of Sciences, 1999

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Molecular basis of fast inactivation in voltage and Ca2+-activated K+ channels: A transmembrane -subunit homolog

Martin Wallner, Meera Pratap

Proceedings of the National Academy of Sciences, 1999

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1 subunits facilitate gating of BK channels by acting through the Ca2+, but not the Mg2+, activating mechanisms

K. L Magleby

Proceedings of the National Academy of Sciences, 2003

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Large conductance Ca 2-activated K (BK) channel: Activation by Ca 2 and voltage

Sebastian Brauchi

Biol. Res, 2006

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Calcium-activated potassium channels

Cecilia Vergara

Current Opinion in Neurobiology, 1998

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Role of the beta1 Subunit in Large-Conductance Ca2+-activated K+ Channel Gating Energetics: Mechanisms of Enhanced Ca2+ Sensitivity

Richard Aldrich

The Journal of General Physiology, 2000

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Determinant for -subunit regulation in high-conductance voltage-activated and Ca2+-sensitive K+ channels: An additional transmembrane region at the N terminus

Martin Wallner, Meera Pratap

Proceedings of the National Academy of Sciences, 1996

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Calcium activation of BKCa potassium channels lacking the calcium bowl and RCK domains

Richard Aldrich

Nature, 2002

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Structure, Gating and Basic Functions of the Ca2+-activated K Channel of Intermediate Conductance

Luigi Catacuzzeno

Current neuropharmacology, 2018

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Mechanisms of K + Channel Regulation

Gerda Breitwieser

Journal of Membrane Biology, 1996

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Molecular Determinants of BK Channel Functional Diversity and Functioning

Osvaldo Alvarez

Physiological Reviews, 2016

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Calcium-driven regulation of voltage-sensing domains in BK channels

Ramon Latorre

2019

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Structure of the human BK channel Ca2+-activation apparatus at 3.0 A resolution

Alexander Pico

Science (New York, N.Y.), 2010

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Ca2+/calmodulin regulates Kvβ1.1-mediated inactivation of voltage-gated K+ channels

Roland Schönherr

Scientific Reports, 2015

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Modulation of calcium-activated potassium channels

Anton Hermann

Journal of Comparative Physiology A, 2002

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beta1-Subunit of the Ca2+-activated K+ channel regulates contractile activity of mouse urinary bladder smooth muscle

Georgi Petkov

The Journal of Physiology, 2001

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International Union of Pharmacology. LII. Nomenclature and Molecular Relationships of Calcium-Activated Potassium Channels

Stephan Grissmer, K. Chandy

Pharmacological Reviews, 2005

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Controlling potassium channel activities: Interplay between the membrane and intracellular factors

Yu-fung Lin

Proceedings of the National Academy of Sciences of the United States of America, 2001

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Molecular mechanism underlying β1 regulation in voltage- and calcium-activated potassium (BK) channels

alan neely

Proceedings of the National Academy of Sciences of the United States of America, 2015

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BK potassium channel modulation by leucine-rich repeat-containing proteins

Richard Aldrich

Proceedings of the National Academy of Sciences, 2012

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A BK (Slo1) channel journey from molecule to physiology

Gonzalo Ferreira

Channels, 2013

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Determinant for β-subunit regulation in high-conductance voltage-activated and Ca 2+ -sensitive K + channels: An additional transmembrane region at the N terminus

Meera Pratap

Proceedings of the National Academy of Sciences, 1996

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Molecular determinants of Ca2+-dependent K+ channel function in rat dorsal vagal neurones

Anna Kulik

The Journal of Physiology, 2000

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The beta Subunit Increases the Ca2+ Sensitivity of Large Conductance Ca2+-activated Potassium Channels by Retaining the Gating in the Bursting States

K. L Magleby

The Journal of General Physiology, 1999

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Stepwise contribution of each subunit to the cooperative activation of BK channels by Ca2+

K. L Magleby

Proceedings of the National Academy of Sciences of the United States of America, 2002

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An allosteric modulator activates BK channels by perturbing coupling between Ca2+ binding and pore opening

Carlota Abella

Nature Communications, 2022

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Channelopathy of small- and intermediate-conductance Ca2+-activated K+ channels

Myles Downey

Acta Pharmacologica Sinica

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Primary Sequence and Immunological Characterization of the β-subunit of the High-Conductance Ca++-activated K+ Channel from Smooth Muscle

McHardy Smith, G. Kaczorowski

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