Molecular mechanisms of Aspergillus flavus secondary metabolism and development (original) (raw)

2014, Fungal Genetics and Biology

The plant and human opportunistic fungus Aspergillus flavus is recognized for the production of the carcinogen aflatoxin. Although many reviews focus on the wealth of information known about aflatoxin biosynthesis, few articles describe other genes and molecules important for A. flavus development or secondary metabolism. Here we compile the most recent work on A. flavus secondary metabolite clusters, environmental response mechanisms (stress response pathways, quorum sensing and G protein signaling pathways) and the function of the transcriptional regulatory unit known as the Velvet Complex. A comparison to other Aspergilli reveals conservation in several pathways affecting fungal development and metabolism.

Sign up for access to the world's latest research.

checkGet notified about relevant papers

checkSave papers to use in your research

checkJoin the discussion with peers

checkTrack your impact