Glucocorticoid (GC) sensitivity and GC receptor expression differ in thymocyte subpopulations (original) (raw)

Antigen and glucocorticoid hormone (GC) induce positive selection of DP thymocytes in a TcR transgenic mouse model

Ferenc Boldizsár

Immunology Letters, 2003

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Low glucocorticoid receptor (GR), high Dig2 and low Bcl-2 expression in double positive thymocytes of BALB/c mice indicates their endogenous glucocorticoid hormone exposure

Ferenc Boldizsár

Immunobiology, 2006

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CD4+CD8+TCRlow thymocytes express low levels of glucocorticoid receptors while being sensitive to glucocorticoid-induced apoptosis

Richard Boyd

European Journal of Immunology, 2001

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Killing of immature CD4+CD8+ thymocytes in vivo by anti-CD3 or 5′-(N-ethyl)-carboxamido-adenosine is blocked by glucocorticoid receptor antagonist RU-486

Sam Okret

European Journal of Immunology, 1993

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Conditional Expression of a Glucocorticoid Receptor Transgene in Thymocytes Reveals a Role for Thymic-Derived Glucocorticoids in Thymopoiesis in Vivo

Sam Okret

Endocrinology, 2005

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The glucocorticoid receptor mediates the thymic epithelial cell-induced apoptosis of CD4+8+ thymic lymphoma cells

Ronit v. Sionov

Cellular Immunology, 2004

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Glucocorticoid receptor deficient thymic and peripheral T cells develop normally in adult mice

Andrew Lew

European Journal of Immunology, 2002

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Glucocorticoid-mediated regulation of thymic dendritic cell function

Juan Jose Muñoz

International Immunology, 1999

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Partial blockade of T-cell differentiation during ontogeny and marked alterations of the thymic microenvironment in transgenic mice with impaired glucocorticoid receptor function

Agustin Gregorio Zapata Gonzalez, B. Marchetti

Journal of Neuroimmunology, 1999

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The Mature, Mitogen-Responsive, Human Thymocyte Population Comprises Two Functionally Distinct T-Cell Subsets Differing in Exogenous Interleukin Requirements for Mitogenesis and in Sensitivity to Glucocorticoids

Mauro Piantelli

Scandinavian Journal of Immunology, 2006

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The glucorcorticoid receptor is increased in Atm−/− thymocytes and in Atm−/− thymic lymphoma cells, and its nuclear translocation counteracts c-myc expression

William Lynn

Steroids, 2007

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Glucocorticoid receptors and corticosensitivity of human thymocytes at discrete stages of intrathymic differentiation

Mauro Piantelli

Journal of Immunology, 1987

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Intrathymic T Cell Development and Selection Proceeds Normally in the Absence of Glucocorticoid Receptor Signaling

Richard Boyd

Immunity, 2000

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Glucocorticoid Resistance in Thymocytes from Mice Expressing a T Cell Receptor Transgene

Sam Okret

Biochemical and Biophysical Research Communications, 2000

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Glucocorticoid production in the murine thymus

Richard Boyd

European Journal of Immunology, 2000

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Glucocorticoid receptors and cortico-sensitivity in a human clonal monocytic cell line, CM-SM

Mauro Piantelli

Journal of Cellular Physiology, 1983

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A targeted glucocorticoid receptor antisense transgene increases thymocyte apoptosis and alters thymocyte development

David H Margulies

Immunity, 1995

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Different roles for glucocorticoids in thymocyte homeostasis?

Sam Okret

Trends in Immunology, 2004

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Developmental shift in TcR-mediated rescue of thymocytes from glucocorticoid-induced apoptosis

Ferenc Boldizsár

Immunobiology, 2008

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Thymocyte Apoptosis Induced by T Cell Activation Is Mediated by Glucocorticoids In Vivo

Judson Brewer

The Journal of Immunology, 2002

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Green Fluorescent Protein-Glucocorticoid Receptor Knockin Mice Reveal Dynamic Receptor Modulation During Thymocyte Development

Louis Muglia, Judson Brewer

The Journal of Immunology, 2002

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In Vivo Resistance to Glucocorticoid-Induced Apoptosis in Rat Thymocytes with Normal Steroid Receptor Function in Vitro

John Cidlowski

Endocrinology, 1997

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The Generation of Mature, Single-Positive Thymocytes In Vivo Is Dysregulated by CD69 Blockade or Overexpression

Steven Ziegler

The Journal of Immunology, 2002

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Glucocorticoid receptors in corticosensitive and corticoresistant thymocyte subpopulations

Mireille Dardenne

Biochimica et Biophysica Acta (BBA) - General Subjects, 1977

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Characterization of thymocyte phenotypic alterations induced by long-lasting β-adrenoceptor blockade in vivo and its effects on thymocyte proliferation and apoptosis

Nevena Arsenovic-Ranin

Molecular and Cellular Biochemistry, 2006

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Increased p300 Expression Inhibits Glucocorticoid Receptor-T-Cell Receptor Antagonism but Does Not Affect Thymocyte Positive Selection

Ming-Zong Lai

Molecular and Cellular Biology, 2002

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Glucocorticoids, master modulators of the thymic catecholaminergic system?

Milica Nanut

Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas / Sociedade Brasileira de Biofisica ... [et al.], 2010

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Glucocorticoid receptors and in vitro corticosensitivity in human thymoma

franco oreste ranelletti

Cancer Research, 1980

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Glucocorticoid hormone differentially modulates the in vitro expansion and cytokine profile of thymic and splenic Treg cells

Ramona Pap

Immunobiology, 2019

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β-Selection: Abundance of TCRβ–/γδ– CD44–CD25– (DN4) cells in the foetal thymus

Johannes Dessens, Tessa Crompton

European Journal of Immunology, 2007

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