Insulin and insulin-like growth factor I signalling in neurons (original) (raw)
2007, Frontiers in Bioscience
AI-generated Abstract
Insulin-like peptides play a crucial role in various biological processes, particularly in the brain, where their signaling mechanisms impact neuronal growth and function. This paper examines the sources, biological pathways, and cooperative actions of insulin and insulin-like growth factor I (IGF-I) within the brain, focusing on their implications in neuroprotection, metabolic regulation, and cognitive functions. The significance of these hormones extends to potential therapeutic applications for various brain diseases, emphasizing the need for further research on their cellular and molecular pathways.
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