Efavirenz-Induced Decrease in Plasma Amprenavir Levels in Human Immunodeficiency Virus-Infected Patients and Correction by Ritonavir (original) (raw)

Antimicrobial Agents and Chemotherapy, 2000

Abstract

... with 90% inhibitory concentrations of 40 and 250 ng/ml without and with 50% human serum, respectively; its mean trough plasma level (daily dose of 1,200 mg twice a day [bid]) is 250 ± 200 ng/ml (1, 3–5; S. Piscitelli, S. Vogel, B. Sadler, W. Fiske, L. Metcalf, H. Masur, and J ...

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